SCHEMBL471957

SCHEMBL471957

O=C(O)CCCCC(C(C(=O)O)(N1C(=O)CCC1=O)S(=O)(=O)O)S(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 7/20 0.31
PTGER3 P43115 6/20 0.31
PTGER2 P43116 5/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30450664 0.84
SCHEMBL28546521 0.82 KMT2A (0.30)
SCHEMBL949639 0.72
Ethylene Glycol SCHEMBL3631014 0.70
SCHEMBL6456312 0.70 ALDH1A1 (0.35) PTGER3PTGER2
Octanedioate SCHEMBL29452953 0.70 ALDH1A1 (0.35) PTGER3PTGER2
SCHEMBL8818958 0.70 FABP4 (0.32)
SCHEMBL5441572 0.69 ALDH1A1 (0.35) PTGER3PTGER2
SCHEMBL557138 0.67 TSHR (0.40) PTGER3PTGER2
SCHEMBL1943663 0.67 TSHR (0.40) PTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2097752-B1 METHOD FOR THE PURIFICATION OF AT LEAST ONE TARGET SUBSTANCE THAT IS TO BE IDENTIFIED PETER JOCHEN (DE) 2011-05-18 EP claimed
EP-2097752-A2 METHOD FOR THE PURIFICATION OF AT LEAST ONE TARGET SUBSTANCE THAT IS TO BE IDENTIFIED Peter, Jochen (DE) 2009-09-09 EP claimed
WO-2008055671-A2 METHOD FOR THE PURIFICATION OF AT LEAST ONE TARGET SUBSTANCE THAT IS TO BE IDENTIFIED STEINBEIS GMBH & CO KG FUER TE (DE) 2008-05-15 WO claimed
EP-0882448-B1 Method of encapsulating biologically active agents within erythrocytes and apparatus therefor DIDECO SRL (IT) 2005-01-12 EP claimed
EP-0856055-A1 STREPTAVIDIN MUTANTS TRUSTEES OF BOSTON UNIVERSITY (US) 1998-08-05 EP claimed
WO-1997011183-A1 STREPTAVIDIN MUTANTS TRUSTEES OF BOSTON UNIVERSITY (US) 1997-03-27 WO claimed
US-20220306710-A1 TREATING ALZHEIMER'S DISEASE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-09-29 US disclosed
EP-4061396-A1 TREATING ALZHEIMER'S DISEASE Yeda Research and Development Co. Ltd (IL) 2022-09-28 EP disclosed
US-20200384130-A1 B-CELL MATURATION ANTIGEN (BCMA)-DIRECTED NANOPARTICLES DANA-FARBER CANCER INSTITUTE, INC. (US) 2020-12-10 US disclosed
EP-3638319-A1 B-CELL MATURATION ANTIGEN (BCMA)-DIRECTED NANOPARTICLES Dana-Farber Cancer Institute, Inc. (US) 2020-04-22 EP disclosed
CN-106170564-B Proximity assays based on detection of Hybrid Chain Reaction (HCR) 欧凌科生物科技公司 2020-01-03 CN disclosed
WO-2018231949-A1 B-CELL MATURATION ANTIGEN (BCMA)-DIRECTED NANOPARTICLES DANA-FARBER CANCER INSTITUTE, INC. (US) 2018-12-20 WO disclosed
CN-105452466-A Aptamers and uses thereof CARIS LIFE SCIENCES SWITZERLAND HOLDINGS S A R L 2016-03-30 CN disclosed
EP-1316594-A1 Silane group containing polymers Bayer Aktiengesellschaft (DE) 2003-06-04 EP disclosed
US-20020018751-A1 CELLULAR AND SERUM PROTEIN ANCHORS FOR DIAGNOSTIC IMAGING CONJUCHEM, INC. (CA) 2002-02-14 US disclosed
US-20020009441-A1 Reactively modified therapeutic compounds having an extended lifetime in vivo POULETTY PHILIPPE (US) 2002-01-24 US disclosed
US-6022951-A MODIFIED ANTIBIOTIC PEPTIDE FOR INCREASED OR DECREASED SENSITIVITY TO BIOTIN, AND METHODS FOR UTILIZING THESE PROTEINS IN DETECTION, ISOLATION AND PURIFICATION TECHNIQUES U.S. DEPARTMENT OF ENERGY 2000-02-08 US disclosed
EP-0856055-A1 STREPTAVIDIN MUTANTS TRUSTEES OF BOSTON UNIVERSITY (US) 1998-08-05 EP disclosed
WO-1997011183-A1 STREPTAVIDIN MUTANTS TRUSTEES OF BOSTON UNIVERSITY (US) 1997-03-27 WO disclosed
EP-0304934-A2 Labelled molecular probes, their production and use Hunger, Hans-Dieter (DE) 1989-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020018751-A1 CELLULAR AND SERUM PROTEIN ANCHORS FOR DIAGNOSTIC IMAGING FABP3, VCAM1, TAGLN2 PTGER4 4021/4885PTGER3 3493/4885PTGER2 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.