Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852289 | 0.87 | CA1 (0.40) | TDP1SIGMAR1 | |
| SCHEMBL6637468 | 0.83 | SIGMAR1 (0.51) | TDP1L3MBTL1SIGMAR1CES1NAAA | |
| SCHEMBL8048487 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1SIGMAR1NAAA | |
| SCHEMBL7449055 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1SIGMAR1NAAA | |
| SCHEMBL626848 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1SIGMAR1NAAA | |
| SCHEMBL7448881 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1SIGMAR1NAAA | |
| SCHEMBL7449325 | 0.76 | TDP1 (0.61) | TDP1L3MBTL1SIGMAR1NAAA | |
| SCHEMBL198056 | 0.74 | IDO1 (0.58) | TDP1L3MBTL1SIGMAR1 | |
| SCHEMBL14763684 | 0.73 | TDP1 (0.54) | TDP1L3MBTL1SIGMAR1CES1FAAH | |
| SCHEMBL9670319 | 0.73 | TDP1 (0.54) | TDP1L3MBTL1SIGMAR1CES1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148853-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008128711-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | WO | disclosed |
| EP-0947513-B1 | TRICYCLIC AMINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6586604-B2 | Antimicrobial activity versus gram negative and gram positive bacteria | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-07-01 | — | — | US | disclosed |
| US-6384050-B1 | GASTROINTESTINAL DISORDERS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| US-20010037030-A1 | Tricyclic amine derivatives | TAKEMURA MAKOTO (JP) | 2001-11-01 | — | — | US | disclosed |
| EP-0947513-A1 | TRICYCLIC AMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010037030-A1 | Tricyclic amine derivatives | Q6ZSR9, TOP2A, TOP1 | TDP1 1366/4885L3MBTL1 2263/4885SIGMAR1 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.