Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL2532416 | 0.93 | L3MBTL1 (0.43) | KDM4ERECQLADRB2ALDH1A1PKM | |
| Bromide SCHEMBL2534872 | 0.93 | KDM4E (0.42) | KDM4ERECQLADRB2ALDH1A1PKM | |
| Hydrogen Sulfide SCHEMBL3631297 | 0.93 | KDM4E (0.42) | KDM4ERECQLADRB2ALDH1A1PKM | |
| Ammonia Solution, Strong SCHEMBL733845 | 0.93 | KDM4E (0.42) | KDM4ERECQLADRB2ALDH1A1PKM | |
| Fluoride SCHEMBL25246136 | 0.93 | KDM4E (0.42) | KDM4ERECQLADRB2ALDH1A1PKM | |
| Iodide SCHEMBL1835511 | 0.93 | KDM4E (0.42) | KDM4ERECQLADRB2ALDH1A1PKM | |
| SCHEMBL7790112 | 0.93 | KDM4E (0.42) | KDM4ERECQLADRB2ALDH1A1PKM | |
| SCHEMBL26967079 | 0.93 | KDM4E (0.42) | KDM4ERECQLADRB2ALDH1A1PKM | |
| Bromide SCHEMBL1831097 | 0.90 | L3MBTL1 (0.42) | KDM4ERECQLADRB2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164835-A2 | PROCESS FOR PREPARING TRIAZOLONES | F. Hoffmann-Roche AG (CH) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008145563-A2 | PROCESS FOR PREPARING TRIAZOLONES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-04 | — | — | WO | disclosed |