SCHEMBL7790112

SCHEMBL7790112

COCCNCCNCCOC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.42
RECQL P46063 1/20 0.42
ADRB2 P07550 1/20 0.41
ALDH1A1 P00352 8/20 0.39
PKM P14618 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HTT P42858 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
TSHR P16473 2/20 0.36
ATM Q13315 1/20 0.34
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11119 0.96
Hydrochloric Acid SCHEMBL2532416 0.93 L3MBTL1 (0.43) KDM4ERECQLADRB2ALDH1A1PKM
Bromide SCHEMBL2534872 0.93 KDM4E (0.42) KDM4ERECQLADRB2ALDH1A1PKM
SCHEMBL26967079 0.93 KDM4E (0.42) KDM4ERECQLADRB2ALDH1A1PKM
SCHEMBL3631301 0.93 KDM4E (0.42) KDM4ERECQLADRB2ALDH1A1PKM
Fluoride SCHEMBL25246136 0.93 KDM4E (0.42) KDM4ERECQLADRB2ALDH1A1PKM
Iodide SCHEMBL1835511 0.93 KDM4E (0.42) KDM4ERECQLADRB2ALDH1A1PKM
Hydrogen Sulfide SCHEMBL3631297 0.93 KDM4E (0.42) KDM4ERECQLADRB2ALDH1A1PKM
Ammonia Solution, Strong SCHEMBL733845 0.93 KDM4E (0.42) KDM4ERECQLADRB2ALDH1A1PKM
Fluoride SCHEMBL1195814 0.90 KDM4E (0.41) KDM4ERECQLADRB2ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0669946-B2 POLYMER PRODUCTION UNION CARBIDE CHEM PLASTIC (US) 2001-12-19 EP disclosed
EP-0669946-B1 POLYMER PRODUCTION UNION CARBIDE CHEM PLASTIC (US) 1998-07-01 EP disclosed
EP-0449519-B1 Process for producing an impact copolymer SHELL OIL CO (US) 1996-05-08 EP disclosed
EP-0669946-A1 POLYMER PRODUCTION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-09-06 EP disclosed
WO-1995007943-A1 POLYMER PRODUCTION SHELL OIL COMPANY (US) 1995-03-23 WO disclosed
US-5118757-A Preventing fouling of recycle loop by adding alkylene compound to deactivate catalyst SHELL OIL COMPANY (US) 1992-06-02 US disclosed
EP-0449519-A2 Process for producing an impact copolymer SHELL OIL COMPANY (US) 1991-10-02 EP disclosed