SCHEMBL3632076

SCHEMBL3632076

CC(C)(C)c1ccc(P(c2[c]c3ccccc3cc2)c2ccc(C(C)(C)C)cc2)cc1.CC(C)(C)c1ccc(P(c2[c]c3ccccc3cc2)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 0.33
MAP3K5 Q99683 1/20 0.32
NR1I2 O75469 1/20 0.32
LMNA P02545 1/20 0.32
ADRA2A P08913 1/20 0.32
CYP2D6 P10635 1/20 0.32
ACHE P22303 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
KCNH2 Q12809 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
TSHR P16473 1/20 0.31
HSD11B1 P28845 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1462239 0.86
SCHEMBL1443600 0.82 CYP2A6 (0.35)
SCHEMBL234550 0.81 CYP3A4 (0.42)
SCHEMBL356683 0.81 CYP3A4 (0.42)
SCHEMBL4619337 0.80 CYP3A4 (0.41)
SCHEMBL16180769 0.80 CYP3A4 (0.41)
SCHEMBL1460886 0.76 CYP2A6 (0.35)
SCHEMBL2229896 0.74 KDM4E (0.37) TSHRMAPT
SCHEMBL7592241 0.74 SMN1; SMN2 (0.40) LMNACYP2D6TSHRMAPT
SCHEMBL5330004 0.73 ESR1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2158154-A1 METHOD FOR THE PRODUCTION OF HYDROGEN FROM AMMONIA BORANE Kanata Chemical Technologies Inc. (CA) 2010-03-03 EP disclosed
WO-2008141439-A1 METHOD FOR THE PRODUCTION OF HYDROGEN FROM AMMONIA BORANE KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2008-11-27 WO disclosed