Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234550 | 0.80 | CYP3A4 (0.42) | TDP1KDM4E | |
| SCHEMBL356683 | 0.80 | CYP3A4 (0.42) | TDP1KDM4E | |
| SCHEMBL16180769 | 0.79 | CYP3A4 (0.41) | TDP1KDM4E | |
| SCHEMBL4619337 | 0.79 | CYP3A4 (0.41) | TDP1KDM4E | |
| SCHEMBL1443600 | 0.78 | CYP2A6 (0.35) | TDP1CYP1A2 | |
| SCHEMBL7545617 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRPOLBCYP2D6LMNA | |
| SCHEMBL5330004 | 0.75 | ESR1 (0.36) | TDP1 | |
| SCHEMBL9845752 | 0.75 | TSHR (0.42) | SMN1; SMN2TSHRPOLBCYP2D6LMNA | |
| SCHEMBL3632076 | 0.74 | HSD17B2 (0.33) | TSHRCYP2D6LMNAMAPT | |
| SCHEMBL27727906 | 0.71 | SNCA (0.45) | SMN1; SMN2TSHRPOLBCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020022736-A1 | Production of nitriles via hydrocyanation of ethylenically unsaturated organic compounds | RHODIA FIBER AND RESIN INTERMEDIATES (FR) | 2002-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022736-A1 | Production of nitriles via hydrocyanation of ethylenically unsaturated organic compounds | NOS2, NOS1, NOS3 | SMN1; SMN2 2359/4885TSHR 4856/4885POLB 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.