SCHEMBL4619337

SCHEMBL4619337

[Ru].[c]1c(P(c2ccccc2)c2ccccc2)ccc2ccccc12.[c]1c(P(c2ccccc2)c2ccccc2)ccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL356683 0.98 CYP3A4 (0.42) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL234550 0.98 CYP3A4 (0.42) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL16180769 0.96 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL5330004 0.88 ESR1 (0.36) CYP3A4TDP1ESR1ESR2
SCHEMBL4744273 0.84 CYP3A4 (0.31) CYP3A4TDP1
SCHEMBL1443600 0.84 CYP2A6 (0.35) TDP1
SCHEMBL900597 0.81
SCHEMBL1460886 0.80 CYP2A6 (0.35) CYP3A4TDP1
SCHEMBL3632076 0.80 HSD17B2 (0.33)
SCHEMBL8913546 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080261891-A1 COMPOSITIONS AND METHODS FOR USING SYRINGOPEPTIN 25A AND RHAMNOLIPIDS UTAH STATE UNIVERSITY (US) 2008-10-23 US disclosed
EP-1896444-A2 IMPROVED PROCESSES FOR THE PREPARATION OF PROTECTED -(+)-CATECHIN AND (-)-EPICATECHIN NOMOMERS, FOR COUPLING THE PROTECTED MONOMERS WITH AN ACTIVATED, PROTECTED EPICATECHIN MONOMER, AND FOR THE PREPARATION OF EPICATECHIN-(4 , 8)-EPICATECHIN OR -CATECHIN DIMERS AND THEIR DIGALLATES MARS, INCORPORATED (US) 2008-03-12 EP disclosed
WO-2007005248-A2 IMPROVED PROCESSES FOR THE PREPARATION OF PROTECTED -(+)-CATECHIN AND (-)-EPICATECHIN NOMOMERS, FOR COUPLING THE PROTECTED MONOMERS WITH AN ACTIVATED, PROTECTED EPICATECHIN MONOMER, AND FOR THE PREPARATION OF EPICATECHIN-(4β, 8)-EPICATECHIN OR -CATECHIN DIMERS AND THEIR DIGALLATES MARS, INCORPORATED (US) 2007-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261891-A1 COMPOSITIONS AND METHODS FOR USING SYRINGOPEPTIN 25A AND RHAMNOLIPIDS CHIA, SGPL1, RPS25 CYP3A4 4255/4885TDP1 4286/4885ESR1 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.