Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10587181 | 0.96 | GAA (0.41) | GAAMAPTPLAUCA12CA1 | |
| Nitric Acid SCHEMBL27678209 | 0.86 | MAPT (0.34) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL10612156 | 0.86 | GAA (0.34) | GAAMAPTPLAU | |
| SCHEMBL28067348 | 0.86 | GAA (0.34) | GAAMAPTPLAU | |
| Cyclopentanol SCHEMBL27502970 | 0.83 | GAA (0.32) | GAAMAPTPLAU | |
| SCHEMBL4125447 | 0.77 | PLAU (0.39) | GAAMAPTPLAUCA12CA1 | |
| SCHEMBL30046094 | 0.74 | GAA (0.30) | GAAMAPT | |
| SCHEMBL5612975 | 0.71 | GAA (0.41) | GAAMAPTPLAUCA12CA1 | |
| SCHEMBL30047108 | 0.69 | AXL (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL452418 | 0.68 | GAA (0.48) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574103-A | Imidazo [1,2-a ] pyridine fused 1, 3-benzodiazepine derivative and synthesis method thereof | 湖北科技学院 | 2023-08-11 | — | — | CN | claimed |
| CN-112174901-B | Synthesis method and anticancer activity of 1, 3-benzodiazepine compound | 河南师范大学 | 2022-02-08 | — | — | CN | claimed |
| CN-112174901-A | Synthesis method and anticancer activity of 1, 3-benzodiazepine compound | 河南师范大学 | 2021-01-05 | — | — | CN | claimed |
| CN-105467468-B | A kind of tracer detected for underground hydrological and its preparation method and application | 徐州工程学院 | 2017-10-27 | — | — | CN | claimed |
| CN-105802485-A | Antibacterial type environment-friendly paint and preparation method thereof | 苏州圣谱拉新材料科技有限公司 | 2016-07-27 | — | — | CN | claimed |
| US-8492538-B1 | Cyclodextrin derivative salts | MATOS JOSE R (US) | 2013-07-23 | — | — | US | claimed |
| US-7728007-B2 | Therapeutic amides | WAYNE STATE UNIVERSITY (US) | 2010-06-01 | — | — | US | claimed |
| US-7585863-B2 | Antitumor agents; such as (2-(4-(7-Chloro-2-quinoxalinyl)oxy)propionylamino ethansulfonic acid; {2-{4-(7-Chloro-quinoxalin-2-yloxy)-phenoxy}propionyl amino}acetic acid | WAYNE STATE UNIVERSITY (US) | 2009-09-08 | — | — | US | claimed |
| US-20090076073-A1 | THERAPEUTIC AMIDES | WAYNE STATE UNIVERSITY | 2009-03-19 | — | — | US | claimed |
| EP-1390340-A4 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-07-25 | — | — | EP | claimed |
| EP-1539699-A1 | 4- 7'-HALO-2-QUINO (XA-) LINYLOXY!PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS | WAYNE STATE UNIVERSITY (US) | 2005-06-15 | — | — | EP | claimed |
| US-6867298-B2 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2005-03-15 | — | — | US | claimed |
| CN-1543333-A | Two-part aqueous composition for the oxidation dyeing of hair | P&G | 2004-11-03 | — | — | CN | claimed |
| US-20040132618-A1 | Therapeutic amides | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2004-07-08 | — | — | US | claimed |
| EP-1390340-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-02-25 | — | — | EP | claimed |
| US-20040019216-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-01-29 | — | — | US | claimed |
| WO-2004004651-A2 | THERAPEUTIC AMIDES | WAYNE STATE UNIVERSITY (US) | 2004-01-15 | — | — | WO | claimed |
| WO-2004005260-A1 | A-`7-HALO-2-QUINO (XA-) LINYLOXY!PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS | WAYNE STATE UNIVERSITY (US) | 2004-01-15 | — | — | WO | claimed |
| US-20030065187-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-03 | — | — | US | claimed |
| WO-2002085838-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065187-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | ADH5, CBR3, ALDH3A1 | GAA 2880/4885MAPT 2654/4885PLAU 4540/4885 |
| US-20040019216-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | ADH5, CBR3, ALDH3A1 | GAA 2880/4885MAPT 2654/4885PLAU 4540/4885 |
| US-20040132618-A1 | Therapeutic amides | HDAC5, HDAC6, ASAH2 | GAA 388/4885MAPT 3239/4885PLAU 2246/4885 |
| US-20090076073-A1 | THERAPEUTIC AMIDES | HDAC5, HDAC6, ASAH2 | GAA 417/4885MAPT 3590/4885PLAU 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.