SCHEMBL363301

SCHEMBL363301

FC(F)(F)c1ccccc1Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA5A P35218 1/20 0.54
CA9 Q16790 1/20 0.54
HSD11B1 P28845 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GAA P10253 3/20 0.43
LMNA P02545 2/20 0.43
ALDH1A1 P00352 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
POLB P06746 1/20 0.43
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
IDO1 P14902 2/20 0.40
TSHR P16473 1/20 0.39
TAS2R14 Q9NYV8 2/20 0.38
NFKB1 P19838 1/20 0.38
KIF11 P52732 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29447944 1.00 CA1 (0.54) CA1CA2CA5ACA9HSD11B1
SCHEMBL14127381 1.00 CA1 (0.54) CA1CA2CA5ACA9HSD11B1
SCHEMBL1453604 0.97 CA1 (0.52) CA1CA2CA5ACA9HSD11B1
Water SCHEMBL11569092 0.97 CA1 (0.52) CA1CA2CA5ACA9HSD11B1
Nitrogen SCHEMBL9028084 0.95 CA1 (0.50) CA1CA2CA5ACA9HSD11B1
Nitrogen SCHEMBL9401147 0.93 CA1 (0.48) CA1CA2CA5ACA9HSD11B1
Isothiocyanate SCHEMBL27973971 0.89 CA2 (0.46) CA1CA2CA5ACA9HSD11B1
SCHEMBL27651159 0.87 CA1 (0.58) CA1CA2CA5ACA9HSD11B1
Phenol SCHEMBL28242955 0.87 CA1 (0.46) CA1CA2CA5ACA9HSD11B1
SCHEMBL3675741 0.83 CA1 (0.54) CA1CA2CA5ACA9HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677522-B Preparation method of o-trifluoromethyl benzamide and intermediate thereof 浙江巍华新材料股份有限公司 2025-02-14 CN claimed
CN-118206825-A Electrical appliance protection shell based on high polymer material and manufacturing method thereof 深圳市维高模塑有限公司 2024-06-18 CN claimed
CN-118119583-A Method for producing fluorine-containing aromatic compound 大金工业株式会社 2024-05-31 CN claimed
CN-113754512-B Preparation method of o-bromobenzotrifluoride 浙江巍华新材料股份有限公司 2024-05-17 CN claimed
CN-117843499-A Diamine with asymmetric structure, high-performance polyimide, and preparation methods and applications thereof 华南理工大学 2024-04-09 CN claimed
CN-116623435-B Fabric waterproof agent based on modified fluorosilicone resin and preparation method thereof 天津工大纺织助剂有限公司 2024-01-30 CN claimed
CN-116874458-A Coumarin fluorescent probe based on benzotrifluoride derivative and application thereof 常州大学 2023-10-13 CN claimed
CN-116623435-A Fabric waterproof agent based on modified fluorosilicone resin and preparation method thereof 天津工大纺织助剂有限公司 2023-08-22 CN claimed
CN-115677522-A Preparation method of o-trifluoromethyl benzamide and intermediate thereof 浙江巍华新材料股份有限公司 2023-02-03 CN claimed
CN-111423331-B Photochemical catalytic synthesis method of aryl alkyl ether 北京工商大学 2022-11-11 CN claimed
US-6858315-B2 Low VOC asphalt primer BUILDING MATERIALS INVESTMENT CORPORATION (US) 2005-02-22 US claimed
US-20040245657-A1 Method for the production of Grignard compounds GRUNENTHAL GMBH (DE) 2004-12-09 US claimed
EP-1463737-A1 METHOD FOR THE PRODUCTION OF GRIGNARD COMPOUNDS Grünenthal GmbH (DE) 2004-10-06 EP claimed
US-20040071995-A1 Low VOC asphalt primer BUILDING MATERIALS INVESTMENT CORPORATION 2004-04-15 US claimed
WO-2004029363-A2 LOW VOC ASPHALT PRIMER BUILDING MATERIALS INVESTMENT CORPORATION (US) 2004-04-08 WO claimed
WO-2003055894-A1 METHOD FOR THE PRODUCTION OF GRIGNARD COMPOUNDS Grünenthal GmbH (DE) 2003-07-10 WO claimed
US-5976702-A ORGANOSILICON COMPOUNDS ASAHI GLASS COMPANY LTD. (JP) 1999-11-02 US claimed
CN-1047285-A New phenyl pyrimidine ketone derivatives and preparation method thereof ICI PLC (GB) 1990-11-28 CN claimed
EP-0396250-A1 Pyrimidinone derivatives ZENECA LIMITED (GB) 1990-11-07 EP claimed
US-4968852-A PHOSPHINE-RHODIUM COMPLEX DECARBONYLATION CATALYST CENTRAL GLASS COMPANY, LIMITED (JP) 1990-11-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040245657-A1 Method for the production of Grignard compounds GMNN, MSH2, GRHPR CA1 264/4885CA2 840/4885CA5A 1385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.