Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130950 | 0.80 | SRC (0.41) | SRCALDH1A1LMNACYP2C19CYP2D6 | |
| SCHEMBL438263 | 0.78 | SRC (0.40) | SRCALDH1A1LMNACYP2C19CYP2D6 | |
| SCHEMBL6181171 | 0.77 | ENPP2 (0.46) | LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL3633092 | 0.76 | ALDH1A1 (0.42) | SRCALDH1A1LMNATDP1CYP2C19 | |
| SCHEMBL669211 | 0.76 | SRC (0.54) | SRCALDH1A1LMNAPMP22KMT2A | |
| SCHEMBL9006009 | 0.76 | CA1 (0.42) | SRCALDH1A1DPP4 | |
| SCHEMBL5555043 | 0.76 | SRC (0.39) | SRCALDH1A1LMNACYP2C19CYP2D6 | |
| SCHEMBL9250334 | 0.76 | GBA1 (0.40) | SRCALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL8646919 | 0.76 | KMT2A (0.39) | SRCALDH1A1LMNAPMP22KMT2A | |
| SCHEMBL16604556 | 0.75 | SRC (0.41) | SRCKEAP1ALDH1A1LMNAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1865940-A2 | ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Applera Corporation (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006102243-A2 | ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | APPLERA CORPORATION (US) | 2006-09-28 | — | — | WO | claimed |
| CN-110892568-B | Modified triazine functional compounds | 诺姆斯科技公司 | 2023-03-31 | — | — | CN | disclosed |
| WO-1995009158-A1 | TRICYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1995-04-06 | — | — | WO | disclosed |
| WO-1994007869-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |