SCHEMBL3633166

SCHEMBL3633166

CCNC(=O)NCCN(C)C

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.48
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
KDM4E B2RXH2 1/20 0.43
HTT P42858 2/20 0.42
POLB P06746 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
EPHX1 P07099 5/20 0.41
ALDH1A1 P00352 1/20 0.41
USP2 O75604 1/20 0.40
EPHX2 P34913 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533471 0.91 CA1 (0.50) DNM1CA1CA2CA12CA9
Hydrochloric Acid SCHEMBL10856379 0.88 DNM1 (0.48) DNM1CA1CA2CA12CA9
SCHEMBL60002 0.87 DNM1 (0.53) DNM1KDM4EHTTPOLBMEN1
SCHEMBL8396016 0.86 EPHX1 (0.54) DNM1CA1CA2CA12CA9
SCHEMBL13670125 0.85 EPHX1 (0.52) DNM1KDM4EMEN1KMT2AEPHX1
Water SCHEMBL29264273 0.85 DNM1 (0.51) DNM1KDM4EHTTPOLBMEN1
Hydrochloric Acid SCHEMBL15878572 0.85 DNM1 (0.51) DNM1KDM4EHTTPOLBMEN1
Hydrochloric Acid SCHEMBL218974 0.85 DNM1 (0.51) DNM1KDM4EHTTPOLBMEN1
Iodomethane SCHEMBL4824562 0.84 DNM1 (0.50) DNM1KDM4EHTTPOLBMEN1
SCHEMBL23834129 0.81 EPHX2 (0.40) DNM1KDM4EHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4218722-A2 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS Alnylam Pharmaceuticals, Inc. (US) 2023-08-02 EP disclosed
EP-3860561-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2023-06-21 EP disclosed
EP-2788316-B1 BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2019-04-24 EP disclosed
US-20170233734-A1 NUCLEIC ACID LIPID PARTICLE FORMULATIONS ALNYLAM PHARMACEUTICALS INC (US) 2017-08-17 US disclosed
US-9687448-B2 Nucleic acid lipid particle formulations ALNYLAM PHARMACEUTICALS, INC. (US) 2017-06-27 US disclosed
US-9682922-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2017-06-20 US disclosed
EP-2575764-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2017-04-19 EP disclosed
US-9463247-B2 Branched alkyl and cycloalkyl terminated biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2016-10-11 US disclosed
CN-105949421-A Temperature-sensitive catalyst used for solvent-free polyurethane synthesis, and preparation method thereof 中国科学院福建物质结构研究所 2016-09-21 CN disclosed
US-20160009637-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2016-01-14 US disclosed
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
US-20070112044-A1 Thiadiazoline derivative KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-05-17 US disclosed
US-20070112044-A1 Thiadiazoline derivative KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-05-17 US disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed
US-4097600-A ANTICARIES AGENTS COLGATE PALMOLIVE COMPANY (US) 1978-06-27 US disclosed
US-4082756-A QUATERNARY QUINUCLIDINIUM CARBAMATES AND THIOCARBAMATES COLGATE-PALMOLIVE COMPANY (US) 1978-04-04 US disclosed
US-4038303-A QUATERNARY AMMONIUM CARBAMIDE COMPOUNDS COLGATE-PALMOLIVE COMPANY (US) 1977-07-26 US disclosed
US-4007281-A Pharmaceutical compositions containing quaternary ammonium compounds COLGATE-PALMOLIVE COMPANY (US) 1977-02-08 US disclosed
US-3956479-A ANTICARIES AGENTS, FUNGICIDES, BACTERICIDES, DENTIFRICES, MOUTHWASHES, CARBAMATES, THIOCARBAMATES COLGATE-PALMOLIVE COMPANY (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160009637-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, CETP, APOB DNM1 442/4885CA1 3362/4885CA2 3065/4885
US-20070112044-A1 Thiadiazoline derivative TLK2, TLK1, BRWD1 DNM1 3646/4885CA1 4804/4885CA2 4492/4885
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 DNM1 1159/4885CA1 2542/4885CA2 1930/4885
US-20170233734-A1 NUCLEIC ACID LIPID PARTICLE FORMULATIONS LIPA, ABHD16A, CETP DNM1 984/4885CA1 4797/4885CA2 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.