Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570377 | 0.84 | GAA (0.69) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL6841293 | 0.82 | TSHR (0.64) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL31195256 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL18879566 | 0.79 | TSHR (0.64) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL623427 | 0.78 | MAPT (0.60) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL13588729 | 0.77 | CA1 (0.62) | ALDH1A1KMT2AL3MBTL1HTTCA1 | |
| SCHEMBL11236109 | 0.76 | ALDH1A1 (0.67) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL12012375 | 0.76 | TSHR (1.00) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL4075322 | 0.76 | MAPT (0.64) | ALDH1A1GAAKMT2AMEN1LMNA | |
| Acedapsone SCHEMBL152710 | 0.76 | PKM (0.85) | ALDH1A1GAAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148678-A1 | ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION | Siga Technologies, Inc. (US) | 2010-02-03 | — | — | EP | claimed |
| WO-2008147962-A1 | ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION | SIGA TECHNOLOGIES, INC. (US) | 2008-12-04 | — | — | WO | claimed |