Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.61 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | TYK2 | P29597 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30758571 | 0.98 | PTPN1 (0.65) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL363882 | 0.93 | PTPN1 (0.67) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL16316028 | 0.90 | NPC1 (0.59) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL32688301 | 0.88 | PTPN1 (0.77) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL11772637 | 0.87 | ALDH1A1 (0.68) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL15652067 | 0.87 | ALDH1A1 (0.68) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL126415 | 0.86 | PTPN1 (0.87) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL27480739 | 0.84 | UNG (0.56) | PTPN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14715824 | 0.84 | NPC1 (0.88) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL18103163 | 0.84 | NPC1 (0.88) | PTPN1NPC1RAB9ASIRT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-12-28 | — | — | US | disclosed |
| CN-110357789-B | N-substituted acrylamide derivative as DHODH inhibitor and preparation and application thereof | 华东理工大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-111116464-B | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2022-09-13 | — | — | CN | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-111116464-A | (E) -4- (pyridylformylhydrazono) -N-phenylbenzamide antitumor compounds | 中国医科大学 | 2020-05-08 | — | — | CN | disclosed |
| EP-2417144-B1 | SYNTHESIS OF 2'-O-FUCOSYLLACTOSE | GLYCOM AS (DK) | 2017-08-23 | — | — | EP | disclosed |
| EP-2417143-B1 | SYNTHESIS OF 2'-O-FUCOSYLLACTOSE | GLYCOM AS (DK) | 2016-12-21 | — | — | EP | disclosed |
| US-20160024129-A1 | SYNTHESIS OF NEW SIALOOLIGOSACCHARIDE DERIVATIVES | GLYCOM A/S (DK) | 2016-01-28 | — | — | US | disclosed |
| US-9200142-B2 | Thermoplastic polymer composition | MILLIKEN & COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| US-9200144-B2 | Thermoplastic polymer composition | MILLIKEN & COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| EP-1340750-A1 | AMIDE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-09-03 | — | — | EP | disclosed |
| WO-2003028762-A1 | NOVEL ANTIMICROBIAL RESISTANCE BLOCKING COMPOSITIONS | ETHICON, INC. (US) | 2003-04-10 | — | — | WO | disclosed |
| EP-1165494-A2 | HSV PRIMASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2002-01-02 | — | — | EP | disclosed |
| US-6323202-B1 | BENZAMIDE SUBSTITUTES WITH KETONE COMPOUNDS AS ENZYME INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-11-27 | — | — | US | disclosed |
| WO-2000058270-A2 | HSV PRIMASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-10-05 | — | — | WO | disclosed |
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-3931142-A | Heterocyclic containing disazo compounds | CIBA-GEIGY AG (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024129-A1 | SYNTHESIS OF NEW SIALOOLIGOSACCHARIDE DERIVATIVES | FUCA1, FUT5, FUCA2 | PTPN1 3558/4885NPC1 2003/4885RAB9A 823/4885 |
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | SLC1A5, SLC7A1, SLC7A5 | PTPN1 4141/4885NPC1 161/4885RAB9A 1245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.