Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | MARS1 | P56192 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632388 | 0.85 | TP53 (0.37) | TSHRHSD17B10TP53NOTUMMEN1 | |
| SCHEMBL535999 | 0.79 | MGLL (0.39) | TSHRNOTUMMEN1MAPTKMT2A | |
| SCHEMBL6536889 | 0.72 | BIRC5 (0.41) | TSHRNOTUMMEN1KMT2AHTT | |
| SCHEMBL11574910 | 0.72 | MGLL (0.44) | TP53NOTUMALOX12MEN1MAPT | |
| SCHEMBL4716198 | 0.70 | TP53 (0.44) | TSHRHSD17B10TP53G6PDALOX12 | |
| SCHEMBL3627258 | 0.69 | SMN1; SMN2 (0.33) | TSHRHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL2092013 | 0.69 | L3MBTL1 (0.36) | TP53NOTUMALOX12MEN1MAPT | |
| SCHEMBL2749887 | 0.68 | TP53 (0.38) | TSHRHSD17B10TP53NOTUMG6PD | |
| SCHEMBL2752660 | 0.67 | NOTUM (0.44) | TP53NOTUMALOX12MEN1MAPT | |
| SCHEMBL16719826 | 0.64 | BIRC5 (0.35) | TP53NOTUMALOX12MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144898-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008130021-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-30 | — | — | WO | disclosed |
| WO-2007043677-A9 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2007-06-07 | — | — | WO | disclosed |