Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 7/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628304 | 0.85 | ANO1 (0.57) | ANO1MAPK1RECQLHSD17B10KDM4E | |
| SCHEMBL3534397 | 0.84 | L3MBTL1 (0.65) | ANO1HSD17B10TSHRKDM4ERCE1 | |
| SCHEMBL2294234 | 0.81 | L3MBTL1 (0.55) | ANO1HSD17B10TSHRKDM4ERCE1 | |
| SCHEMBL2294314 | 0.80 | MEN1 (0.62) | ANO1HSD17B10KDM4ERCE1MEN1 | |
| SCHEMBL1918508 | 0.79 | ANO1 (0.57) | ANO1MAPK1RECQLHSD17B10KDM4E | |
| SCHEMBL1918391 | 0.78 | KDM4E (0.59) | ANO1MAPK1RECQLHSD17B10KDM4E | |
| SCHEMBL2404910 | 0.78 | ATM (0.52) | ANO1HSD17B10TSHRKDM4ERCE1 | |
| SCHEMBL29852823 | 0.78 | ATM (0.52) | ANO1HSD17B10TSHRKDM4ERCE1 | |
| SCHEMBL3666856 | 0.76 | ANO1 (0.48) | ANO1KDM4ERCE1MEN1KMT2A | |
| SCHEMBL3539969 | 0.76 | KDM4E (0.79) | ANO1HSD17B10TSHRKDM4ERCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120760-A1 | BENZOFURAN-CARBOXAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANG (IT) | 2010-05-13 | — | — | US | disclosed |
| EP-2146999-A1 | BENZOFURAN- CARBOXAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008125874-A1 | BENZOFURAN- CARBOXAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120760-A1 | BENZOFURAN-CARBOXAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | ZC3HAV1, EIF2AK2, GTF3C1 | ANO1 3186/4885MAPK1 2502/4885RECQL 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.