Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628304 | 0.89 | ANO1 (0.57) | ANO1RCE1MEN1KMT2AMAPT | |
| SCHEMBL3632851 | 0.88 | GAA (0.42) | ANO1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL3633969 | 0.76 | ANO1 (0.57) | ANO1RCE1MEN1KMT2AMAPT | |
| SCHEMBL3534397 | 0.76 | L3MBTL1 (0.65) | ANO1RCE1MEN1KMT2AMAPT | |
| SCHEMBL3631501 | 0.74 | GAA (0.42) | ANO1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL2294314 | 0.73 | MEN1 (0.62) | ANO1RCE1MEN1KMT2AMAPT | |
| SCHEMBL2294234 | 0.73 | L3MBTL1 (0.55) | ANO1RCE1MEN1KMT2AMAPT | |
| SCHEMBL17652429 | 0.72 | KCNH2 (0.42) | — | |
| SCHEMBL2404910 | 0.69 | ATM (0.52) | ANO1RCE1MEN1KMT2AMAPT | |
| SCHEMBL29852823 | 0.69 | ATM (0.52) | ANO1RCE1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146999-A1 | BENZOFURAN- CARBOXAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008125874-A1 | BENZOFURAN- CARBOXAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-10-23 | — | — | WO | disclosed |