Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28531756 | 0.86 | NR1H4 (0.35) | NR1H4KDM4EALDH1A1TDP1AR | |
| SCHEMBL27636812 | 0.79 | THRB (0.46) | KDM4EALDH1A1KMT2APOLBMAPT | |
| SCHEMBL27890886 | 0.79 | ELANE (0.46) | ALDH1A1HTTKMT2ASMN1; SMN2GAA | |
| SCHEMBL5922597 | 0.78 | AR (0.36) | NR1H4KDM4EALDH1A1TDP1AR | |
| SCHEMBL8735250 | 0.76 | MAPT (0.41) | KDM4EALDH1A1TDP1ARHTT | |
| SCHEMBL27946212 | 0.76 | HTT (0.36) | NR1H4KDM4EALDH1A1TDP1AR | |
| SCHEMBL25431706 | 0.74 | LMNA (0.40) | KDM4EALDH1A1TDP1ARHTT | |
| SCHEMBL21802630 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1TDP1ARHTT | |
| SCHEMBL17024119 | 0.72 | HIF1A (0.42) | NR1H4KDM4EALDH1A1TDP1AR | |
| SCHEMBL9418363 | 0.72 | HTT (0.36) | NR1H4KDM4EALDH1A1TDP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593069-B1 | FILLERS FOR DENTAL COMPOSITES | QUARZWERKE GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |
| US-20180015004-A1 | FILLERS FOR DENTAL COMPOSITES | QUARZWERKE GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-20130178552-A1 | FILLERS FOR DENTAL COMPOSITES | QUARZWERKE GMBH (DE) | 2013-07-11 | — | — | US | disclosed |
| EP-2593069-A1 | FILLERS FOR DENTAL COMPOSITES | Quarzwerke GmbH (DE) | 2013-05-22 | — | — | EP | disclosed |
| CN-103079524-A | Filler for dental composites | QUARZWERKE GMBH | 2013-05-01 | — | — | CN | disclosed |
| WO-2012007440-A1 | FILLERS FOR DENTAL COMPOSITES | QUARZWERKE GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
| US-6437019-B1 | Glass ionomer cement | 3M INNOVATIVE PROPERTIES COMPANY | 2002-08-20 | — | — | US | disclosed |
| EP-0906076-A1 | GLASS IONOMER CEMENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997047272-A1 | GLASS IONOMER CEMENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |
| EP-0381153-B1 | Radiopaque fluoride releasing VLC dental composites and the use of specific fillers therein | DENTSPLY INT INC (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5304586-A | Photoactivated resin containing fluoride leachable glass | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0381153-A2 | Radiopaque fluoride releasing VLC dental composites and the use of specific fillers therein | DENTSPLY INTERNATIONAL, INC. (US) | 1990-08-08 | — | — | EP | disclosed |
| US-4491453-A | Process for restoring teeth with visible light curable compositions | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1985-01-01 | — | — | US | disclosed |