SCHEMBL3634458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3741445	0.88	GHSR (0.63)	GHSRSLC1A2SLC1A3SLC1A1KCNH2
	SCHEMBL3634157	0.86	GHSR (0.61)	GHSRSLC1A2SLC1A3SLC1A1KCNH2
	SCHEMBL3634225	0.85	GHSR (0.67)	GHSRABCB1LMNAMAPTTACR1
	SCHEMBL3638183	0.83	GHSR (0.71)	GHSRSLC1A2SLC1A3SLC1A1ABCB1
	SCHEMBL3743921	0.82	GHSR (1.00)	GHSRSLC1A2KCNH2CYP3A4CYP3A5
	SCHEMBL3741670	0.82	GHSR (1.00)	GHSRSLC1A2KCNH2CYP3A4CYP3A5
	SCHEMBL3640133	0.82	GHSR (1.00)	GHSRSLC1A2KCNH2CYP3A4CYP3A5
	SCHEMBL3635981	0.82	GHSR (1.00)	GHSRSLC1A2KCNH2CYP3A4CYP3A5
	SCHEMBL3737852	0.82	GHSR (0.63)	GHSRTACR1
	SCHEMBL3634475	0.82	GHSR (0.71)	GHSRTACR1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.