Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102802 | 0.83 | MAPT (0.42) | MAPTL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL14382270 | 0.73 | TLR8 (0.52) | MAPTL3MBTL1TP53 | |
| SCHEMBL204025 | 0.72 | MAPT (0.35) | MAPTL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL9909829 | 0.72 | NQO2 (0.46) | MAPTL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL16509309 | 0.71 | NLRP3 (0.67) | MAPTALDH1A1LMNATSHRTP53 | |
| SCHEMBL7364726 | 0.70 | MAPT (0.39) | MAPTL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL3634768 | 0.68 | KDM4E (0.37) | MAPTL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL7086885 | 0.66 | NPC1 (0.47) | MAPTL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL28818202 | 0.66 | NQO2 (0.45) | MAPTL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL8426124 | 0.66 | NQO2 (0.45) | MAPTL3MBTL1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155699-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | Merial Limited (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008144275-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2008-11-27 | — | — | WO | disclosed |