3,4-Dihydroxyphenylacetic Acid

3,4-Dihydroxyphenylacetic Acid

SCHEMBL36348

O=C(O)Cc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 1.00
KDM4E B2RXH2 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
HSD17B10 Q99714 3/20 1.00
MAPT P10636 3/20 1.00
TSHR P16473 2/20 1.00
NFKB1 P19838 2/20 1.00
HIF1A Q16665 2/20 1.00
HPGD P15428 2/20 1.00
RGS12 O14924 1/20 1.00
LMNA P02545 1/20 1.00
POLB P06746 1/20 1.00
APEX1 P27695 1/20 1.00
THPO P40225 1/20 1.00
BLM P54132 1/20 1.00
GNAI1 P63096 1/20 1.00
PMP22 Q01453 1/20 1.00
CA2 P00918 3/20 0.68
ALDH1A1 P00352 3/20 0.61
CAMK2A Q9UQM7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4-Dihydroxyphenylacetic Acid SCHEMBL29382155 1.00 GAA (1.00) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL8214151 0.98 GAA (0.96) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL8214147 0.98 GAA (0.96) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL18338957 0.92 GAA (0.85) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL21381267 0.92 GAA (0.85) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL175566 0.89 TDP1 (0.79) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL29246309 0.87 GAA (0.76) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL8565392 0.87 GAA (0.76) GAAKDM4ETDP1HSD17B10MAPT
SCHEMBL2050404 0.84 GAA (0.73) GAAKDM4ETDP1HSD17B10MAPT
SCHEMBL15499982 0.84 GAA (0.73) GAAKDM4ETDP1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6929 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122084713-A Microelectrode, probe and electrochemical detection device 2026-05-26 CN claimed
CN-116473503-B Method for detecting refraction development effect of longitudinal chromatic aberration defocus signal on eyeball 首都医科大学附属北京同仁医院 2026-05-19 CN claimed
US-12616771-B2 Tissue adherent chitosan material that resists dissolution TRICOL BIOMEDICAL, INC. (US) 2026-05-05 US claimed
US-12569451-B2 Bio-inspired tissue-adhesive hydrogel patch and uses thereof Cellartgen Inc. (KR) 2026-03-10 US claimed
US-20260061091-A1 MUSSEL-INSPIRED TISSUE ADHESIVES AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION (US) 2026-03-05 US claimed
EP-4683964-A2 POLY(ETHYLENE GLYCOL) BASED DENDRIMER-LIKE HYPERBRANCHED MACROMOLECULES, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2026-01-28 EP claimed
EP-4665307-A1 BIODEGRADABLE MICROPARTICLES FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2025-12-24 EP claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12383490-B2 Generic high-capacity protein capture and tunable electrochemical release NYCTEA TECHNOLOGIES AB (SE) 2025-08-12 US claimed
EP-0031561-B1 A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT MERCK & CO. INC. (US) 1985-04-10 EP claimed
US-4470980-A Method of increasing oral absorption of β-lactam antibiotics INTERX RESEARCH CORP. (US) 1984-09-11 US claimed
US-4406896-A ANTIBIOTICS, ACIDS, HYDROXY MERCK & CO., INC. (US) 1983-09-27 US claimed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP claimed
US-4279870-A Liquid-liquid extraction process for the recovery of tungsten from low level sources GTE LABORATORIES INCORPORATED (US) 1981-07-21 US claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed
US-4042329-A Method and device for detecting cholesterol BECTON, DICKINSON AND COMPANY (US) 1977-08-16 US claimed
US-3964871-A GLUCOSE OXIDASE, HORSERADISH PEROXIDASE BECTON, DICKINSON AND COMPANY (US) 1976-06-22 US claimed