3,4-Dihydroxyphenylacetic Acid

3,4-Dihydroxyphenylacetic Acid

SCHEMBL29382155

O=C(O)Cc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 1.00
KDM4E B2RXH2 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
HSD17B10 Q99714 3/20 1.00
MAPT P10636 3/20 1.00
TSHR P16473 2/20 1.00
NFKB1 P19838 2/20 1.00
HIF1A Q16665 2/20 1.00
HPGD P15428 2/20 1.00
RGS12 O14924 1/20 1.00
LMNA P02545 1/20 1.00
POLB P06746 1/20 1.00
APEX1 P27695 1/20 1.00
THPO P40225 1/20 1.00
BLM P54132 1/20 1.00
GNAI1 P63096 1/20 1.00
PMP22 Q01453 1/20 1.00
CA2 P00918 3/20 0.68
ALDH1A1 P00352 3/20 0.61
CAMK2A Q9UQM7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4-Dihydroxyphenylacetic Acid SCHEMBL36348 1.00 GAA (1.00) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL8214151 0.98 GAA (0.96) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL8214147 0.98 GAA (0.96) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL18338957 0.92 GAA (0.85) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL21381267 0.92 GAA (0.85) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL175566 0.89 TDP1 (0.79) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL29246309 0.87 GAA (0.76) GAAKDM4ETDP1HSD17B10MAPT
3,4-Dihydroxyphenylacetic Acid SCHEMBL8565392 0.87 GAA (0.76) GAAKDM4ETDP1HSD17B10MAPT
SCHEMBL2050404 0.84 GAA (0.73) GAAKDM4ETDP1HSD17B10MAPT
SCHEMBL15499982 0.84 GAA (0.73) GAAKDM4ETDP1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636402-B2 Chitosan dressing for control of gastrointestinal bleeding TRICOL BIOMEDICAL, INC. (US) 2026-05-26 US disclosed
EP-4181781-B1 BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD UNIV KINDERSPITAL BEIDER BASEL (CH) 2026-05-20 EP disclosed
US-12616771-B2 Tissue adherent chitosan material that resists dissolution TRICOL BIOMEDICAL, INC. (US) 2026-05-05 US disclosed
US-12590065-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS, INC. (US) 2026-03-31 US disclosed
US-12508171-B2 Delivery systems for control of bleeding in transurethral prostatectomy TRICOL BIOMEDICAL, INC. (US) 2025-12-30 US disclosed
EP-4630006-A1 FLOWABLE CHITOSAN BIOADHESIVE HEMOSTATIC COMPOSITIONS THAT RESIST DISSOLUTION Tricol Biomedical, Inc. (US) 2025-10-15 EP disclosed
US-12365025-B2 Fine metal linear body MITSUI MINING & SMELTING CO., LTD. (JP) 2025-07-22 US disclosed
US-12295394-B2 Water-soluble additive composition SUMITOMO BAKELITE CO., LTD. (JP) 2025-05-13 US disclosed
US-12275975-B2 Conversion of lignin into bioplastics and lipid fuels The Texas A&MUniversity System (US) 2025-04-15 US disclosed
WO-2025069904-A1 PROCESSING LIQUID, METHOD FOR PROCESSING OBJECT TO BE PROCESSED, METHOD FOR PROCESSING PAD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE 富士フイルム株式会社 2025-04-03 WO disclosed
US-11564673-B2 Delivery systems for control of gastrointestinal bleeding TRICOL BIOMEDICAL, INC. (US) 2023-01-31 US disclosed
WO-2022261201-A1 DISSOLUTION RESISTANT TISSUE ADHERENT DRESSING APPLICATION AND ITS DELIVERY TRICOL BIOMEDICAL, INC. (US) 2022-12-15 WO disclosed
US-11519011-B2 Conversion of lignin into bioplastics and lipid fuels THE TEXAS A&M UNIVERSITY SYSTEM (US) 2022-12-06 US disclosed
WO-2022122921-A1 PROCESS FOR THE BIOTECHNOLOGICAL PRODUCTION OF 2-PHENYLETHANOLS FROM PLANT SOURCES TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) 2022-06-16 WO disclosed
US-20220175000-A1 WATER-SOLUBLE ADDITIVE COMPOSITION RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH (JP) 2022-06-09 US disclosed
CN-114452274-A Application of plateau catechuic acid in preparing medicine for treating polycystic ovary syndrome 佛山市第一人民医院 2022-05-10 CN disclosed
US-20220096463-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2022-03-31 US disclosed
US-20220089544-A1 DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2022-03-24 US disclosed
EP-3950910-A1 WATER-SOLUBLE ADDITIVE COMPOSITION Sumitomo Bakelite Co.Ltd. (JP) 2022-02-09 EP disclosed
US-11234975-B2 Levorphanol prodrugs and processes for making and using them KEMPHARM, INC. (US) 2022-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636402-B2 Chitosan dressing for control of gastrointestinal bleeding GLS, CDH1, ALPI GAA 1133/4885KDM4E 537/4885TDP1 4487/4885
US-12508171-B2 Delivery systems for control of bleeding in transurethral prostatectomy MUC1, BPHL, KLK3 GAA 2257/4885KDM4E 1478/4885TDP1 2617/4885
US-12590065-B2 Levorphanol prodrugs and processes for making and using them SLC16A3, SLC16A8, SLC16A1 GAA 314/4885KDM4E 1294/4885TDP1 1657/4885
US-11234975-B2 Levorphanol prodrugs and processes for making and using them OPRM1, OPRL1, OPRK1 GAA 2834/4885KDM4E 2657/4885TDP1 1241/4885
US-20220096463-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OPRM1, OPRL1, OPRK1 GAA 2834/4885KDM4E 2657/4885TDP1 1241/4885
US-12616771-B2 Tissue adherent chitosan material that resists dissolution CDH1, DSP, CD63 GAA 2929/4885KDM4E 1411/4885TDP1 2986/4885
US-20220089544-A1 DEXTRORPHAN PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OGFR, OPRM1, CYP4F3 GAA 2142/4885KDM4E 4435/4885TDP1 4008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.