Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL515006 | 0.97 | S1PR4 (0.61) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL29684617 | 0.86 | S1PR4 (0.67) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL19174959 | 0.86 | S1PR4 (0.67) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL358318 | 0.85 | S1PR4 (0.61) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL7957556 | 0.84 | S1PR4 (0.60) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL15005868 | 0.84 | KDM4E (0.64) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL2798909 | 0.83 | S1PR4 (0.59) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL357386 | 0.83 | S1PR4 (0.59) | S1PR4MAPTLMNANPC1RAB9A | |
| SCHEMBL8973132 | 0.83 | CYP19A1 (0.57) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2429316 | 0.83 | ALDH1A1 (0.66) | S1PR4MAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593457-A1 | PYRAZOLO [1, 5A]PYRIMIDINE AND THIENO [3, 2B]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007375-A1 | PYRAZOLO [1, 5A] PYRIMIDINE AND THIENO [3, 2B] PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |
| EP-0362729-A1 | Process for producing water insoluble azo dyes on the fibre | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | disclosed |