Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798909 | 0.92 | S1PR4 (0.59) | S1PR4KDM4EPDE7ALMNANPC1 | |
| SCHEMBL363493 | 0.84 | S1PR4 (0.64) | S1PR4KDM4EPDE7ALMNANPC1 | |
| SCHEMBL19174959 | 0.83 | S1PR4 (0.67) | S1PR4KDM4EPDE7ALMNANPC1 | |
| SCHEMBL29684617 | 0.83 | S1PR4 (0.67) | S1PR4KDM4EPDE7ALMNANPC1 | |
| SCHEMBL357386 | 0.83 | S1PR4 (0.59) | S1PR4KDM4EPDE7ALMNANPC1 | |
| SCHEMBL6575773 | 0.83 | MEN1 (0.56) | S1PR4KDM4ELMNANPC1ALDH1A1 | |
| SCHEMBL8653247 | 0.82 | S1PR4 (0.50) | S1PR4KDM4EPDE7ALMNANPC1 | |
| Hydrochloric Acid SCHEMBL515005 | 0.82 | S1PR4 (0.58) | S1PR4KDM4EPDE7ALMNANPC1 | |
| SCHEMBL358318 | 0.82 | S1PR4 (0.61) | S1PR4KDM4EPDE7ALMNANPC1 | |
| Hydrochloric Acid SCHEMBL515006 | 0.82 | S1PR4 (0.61) | S1PR4KDM4EPDE7ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074403-B1 | FLUORESCENT RED EMITTING FUNCTIONALIZABLE CALCIUM INDICATORS | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2018-01-17 | — | — | EP | disclosed |
| US-9745318-B2 | Fluorescent red emitting functionalizable calcium indicators | PARIS SCIENCES ET LETTRES—QUARTIER LATIN (FR) | 2017-08-29 | — | — | US | disclosed |
| US-9745318-B2 | Fluorescent red emitting functionalizable calcium indicators | PARIS SCIENCES ET LETTRES—QUARTIER LATIN (FR) | 2017-08-29 | — | — | US | disclosed |
| US-20160376441-A1 | FLUORESCENT RED EMITTING FUNCTIONALIZABLE CALCIUM INDICATORS | PARIS SCIENCES ET LETTRES (FR) | 2016-12-29 | — | — | US | disclosed |
| WO-2015078948-A1 | FLUORESCENT RED EMITTING FUNCTIONALIZABLE CALCIUM INDICATORS | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2015-06-04 | — | — | WO | disclosed |
| US-6329523-B1 | FOR ANTIBACTERIAL PHARMACEUTICAL USE, USEFUL FOR IDENTIFYING METAL CHELATING SPECIES FOR ?HEAVY METAL? THERAPY; IMAGING AGENTS | ISIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| US-6207826-B1 | Macrocyclic compounds having nitrogen-containing linkages | ISIS PHARMACEUTICALS, INC. | 2001-03-27 | — | — | US | disclosed |
| US-6197965-B1 | POLYARYLALKYLAMINO-SUBSTITUED PYRIDINE DERIVATIVES; DRUGS, MEDICINE, DIAGNOSTICS | ISIS PHARMACEUTICALS, INC. | 2001-03-06 | — | — | US | disclosed |
| EP-0817787-A4 | NITROGENOUS MACROCYCLIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2000-09-13 | — | — | EP | disclosed |
| WO-1998010286-A1 | METHODS FOR PROCESSING CHEMICAL COMPOUNDS HAVING REACTIVE FUNCTIONAL GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1998-03-12 | — | — | WO | disclosed |
| EP-0817787-A1 | NITROGENOUS MACROCYCLIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030377-A1 | NITROGENOUS MACROCYCLIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376441-A1 | FLUORESCENT RED EMITTING FUNCTIONALIZABLE CALCIUM INDICATORS | ORAI1, CHERP, CACNA1I | S1PR4 4056/4885KDM4E 4422/4885PDE7A 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.