Protocatechualdehyde

Protocatechualdehyde

SCHEMBL36350

O=Cc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 1.00
RAB9A P51151 2/20 1.00
PTGS2 P35354 1/20 1.00
LCK P06239 3/20 0.64
XDH P47989 1/20 0.61
ALDH1A1 P00352 5/20 0.57
ALDH5A1 P51649 3/20 0.57
ABAT P80404 3/20 0.57
HPGD P15428 3/20 0.57
TDP1 Q9NUW8 3/20 0.57
EGFR P00533 2/20 0.57
AOX1 Q06278 1/20 0.57
TRIM24 O15164 1/20 0.57
TRIM33 Q9UPN9 1/20 0.57
POLB P06746 3/20 0.56
BLM P54132 2/20 0.56
GFER P55789 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
ALPL P05186 1/20 0.56
ALPI P09923 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Protocatechualdehyde SCHEMBL9512877 1.00 KDM4E (1.00) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL29349539 1.00 KDM4E (1.00) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL27748932 0.97 KDM4E (0.95) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL27876787 0.97 KDM4E (0.95) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL4072910 0.97 KDM4E (0.95) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL1668848 0.97 KDM4E (0.95) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL29196221 0.95 KDM4E (0.91) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL28808068 0.95 KDM4E (0.91) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL27781791 0.95 KDM4E (0.91) KDM4ERAB9APTGS2LCKXDH
Protocatechualdehyde SCHEMBL11526608 0.93 KDM4E (0.86) KDM4ERAB9APTGS2LCKXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11759 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118252866-B Method for extracting and purifying Phellinus linteus fruiting body phenols in series and application of Phellinus linteus fruiting body phenols in uric acid regulation 湖北省农业科学院农产品加工与核农技术研究所 2026-05-19 CN claimed
CN-122060369-A High-gloss transparent waterproof coating composition suitable for photo printing and preparation method thereof 宿州天之印科技有限公司 2026-05-19 CN claimed
CN-122037577-A Silica gel production and preparation method for humanoid robot cable and application thereof 东莞市朗晟材料科技有限公司 2026-05-15 CN claimed
EP-4727986-A1 ABRASIVE ARTICLE August Rüggeberg GmbH & Co. KG (DE) 2026-04-22 EP claimed
US-20260085054-A1 DERIVATIVE OF HISPIDIN FROM SANGHUANGPORUS SANGHUANG, AND PREPARATION METHOD AND USE THEREOF UNIV CHINA THREE GORGES CTGU (CN) 2026-03-26 US claimed
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 EP claimed
US-20260061091-A1 MUSSEL-INSPIRED TISSUE ADHESIVES AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION (US) 2026-03-05 US claimed
EP-4168255-B1 ELASTOMERIC COMPOSITION COMPRISING A PHENOLIC COMPOUND AND A COMPOUND FROM THE MONOSACCHARIDE FAMILY MICHELIN & CIE (FR) 2026-03-04 EP claimed
US-20260028770-A1 SURFACE MODIFIED MICROCAPSULES INT FLAVORS & FRAGRANCES INC (US) 2026-01-29 US claimed
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
EP-0041827-B1 A N-(BENZYLIDENE) AMINOMETHYL-CYCLOHEXANE-CARBOXYLIC ACID KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-03-21 EP claimed
US-4435601-A OXIDATION WITH HYDROGEN PEROXIDE IN ALKALI OR ALKALINE METAL BASE RHONE-POULENC INDUSTRIES (FR) 1984-03-06 US claimed
US-4391603-A HAIR DYES L'OREAL (FR) 1983-07-05 US claimed
EP-0075629-A1 Imidazole derivatives, their preparation, and their pharmaceutical compositions Sumitomo Chemical Industries Ltd. (JP) 1983-04-06 EP claimed
EP-0074725-A1 A method for the production of nuclear substituted cinnamoylanthranilic acid derivatives and intermediates thereof Kissei Pharmaceutical Co. Ltd. (JP) 1983-03-23 EP claimed
EP-0041827-A2 A N-(benzylidene) aminomethyl-cyclohexane-carboxylic acid KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-12-16 EP claimed
EP-0039130-A1 Aromatic compounds as oxygen scavengers in an aqueous medium BETZ EUROPE, INC. (US) 1981-11-04 EP claimed
US-4165341-A FROM CATECHOL OR A 2-ALKOXYPHENOL AND GLYCOLIC ACID USING ALUMINA OR SILICA CATALYST, OXIDATION UBE INDUSTRIES, LTD. (JP) 1979-08-21 US claimed
US-4145255-A ENZYMATIC OXIDATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1979-03-20 US claimed
US-3957424-A Enzyme-activated oxidative process for coloring hair THE PROCTER & GAMBLE COMPANY (US) 1976-05-18 US claimed