Protocatechualdehyde

Protocatechualdehyde

SCHEMBL4072910

O=Cc1ccc(O)c(O)c1.[Si]

nearest known ligand 0.95

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.95
RAB9A P51151 2/20 0.95
PTGS2 P35354 1/20 0.95
LCK P06239 3/20 0.61
ALDH1A1 P00352 5/20 0.61
ALDH5A1 P51649 3/20 0.61
ABAT P80404 3/20 0.61
HPGD P15428 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
AOX1 Q06278 1/20 0.61
TRIM24 O15164 1/20 0.61
TRIM33 Q9UPN9 1/20 0.61
XDH P47989 1/20 0.59
EGFR P00533 2/20 0.55
POLB P06746 3/20 0.54
BLM P54132 2/20 0.54
GFER P55789 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
ALPL P05186 1/20 0.54
ALPI P09923 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Protocatechualdehyde SCHEMBL27748932 1.00 KDM4E (0.95) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL9512877 0.97 KDM4E (1.00) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL29349539 0.97 KDM4E (1.00) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL36350 0.97 KDM4E (1.00) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL27876787 0.95 KDM4E (0.95) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL1668848 0.95 KDM4E (0.95) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL28808068 0.93 KDM4E (0.91) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL29196221 0.93 KDM4E (0.91) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL27781791 0.93 KDM4E (0.91) KDM4ERAB9APTGS2LCKALDH1A1
Protocatechualdehyde SCHEMBL11526608 0.91 KDM4E (0.86) KDM4ERAB9APTGS2LCKALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445118-B2 Coating liquid, metal compound film formed by coating liquid, and forming method thereof CENTRAL JAPAN RAILWAY COMPANY (JP) 2013-05-21 US disclosed
US-20090324963-A1 COATING LIQUID, METAL COMPOUND FILM FORMED BY COATING LIQUID, AND FORMING METHOD THEREOF CENTRAL JAPAN RAILWAY COMPANY (JP) 2009-12-31 US disclosed
EP-2048111-A1 COATING LIQUID, METAL COMPOUND THIN FILM FORMED BY USING COATING LIQUID, AND METHOD FOR FORMING THE SAME Central Japan Railway Company (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324963-A1 COATING LIQUID, METAL COMPOUND FILM FORMED BY COATING LIQUID, AND FORMING METHOD THEREOF F11, F12, CXXC4 KDM4E 232/4885RAB9A 1277/4885PTGS2 4047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.