Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | LCK | P06239 | 3/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.57 |
| ▸ | ABAT | P80404 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.57 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.57 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Protocatechualdehyde SCHEMBL29349539 | 1.00 | KDM4E (1.00) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL36350 | 1.00 | KDM4E (1.00) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL27748932 | 0.97 | KDM4E (0.95) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL27876787 | 0.97 | KDM4E (0.95) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL4072910 | 0.97 | KDM4E (0.95) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL1668848 | 0.97 | KDM4E (0.95) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL29196221 | 0.95 | KDM4E (0.91) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL28808068 | 0.95 | KDM4E (0.91) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL27781791 | 0.95 | KDM4E (0.91) | KDM4ERAB9APTGS2LCKXDH | |
| Protocatechualdehyde SCHEMBL11526608 | 0.93 | KDM4E (0.86) | KDM4ERAB9APTGS2LCKXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108524939-B | Application of mitochondria complex I reversible inhibitor and active oxygen scavenger in preparation of ischemia-reperfusion injury protection medicine | 中国药科大学 | 2019-10-11 | — | — | CN | disclosed |
| CN-109331000-A | Mitochondrial complex I reversible inhibitor combines the purposes for preparing ischemical reperfusion injury protection drug with active oxygen scavenger | 中国药科大学 | 2019-02-15 | — | — | CN | disclosed |
| CN-108524939-A | Application of mitochondria complex I reversible inhibitor and active oxygen scavenger in preparation of ischemia-reperfusion injury protection medicine | 中国药科大学 | 2018-09-14 | — | — | CN | disclosed |
| CN-105250246-B | Application of the protocatechualdehyde in treatment male sterility and extracorporeal treatment sperm | 华北理工大学 | 2017-12-15 | — | — | CN | disclosed |
| EP-0357092-B1 | Preparation of diacetoxybenzylidene diacetates | KUREHA CHEMICAL IND CO LTD (JP) | 1993-10-27 | — | — | EP | disclosed |
| EP-0357092-A1 | Preparation of diacetoxybenzylidene diacetates | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4758591-A | Dialkanoyloxybenzylidene dialkanoate | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-07-19 | — | — | US | disclosed |
| EP-0147174-A2 | Dihydroxybenzaldehyde derivatives as anti-inflammatory agents | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-07-03 | — | — | EP | disclosed |