SCHEMBL363525

SCHEMBL363525

C=Cc1ccc(C(=O)O)nc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 14/20 0.62
P4HA1 P13674 1/20 0.53
MIF P14174 1/20 0.53
KDM4E B2RXH2 4/20 0.52
ALDH1A1 P00352 3/20 0.52
L3MBTL1 Q9Y468 4/20 0.46
KMT2A Q03164 2/20 0.46
HIF1A Q16665 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
THPO P40225 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4144524 0.82 P4HTM (0.43) P4HTMP4HA1MIFKDM4EALDH1A1
SCHEMBL14313758 0.82 KMT2A (0.49) P4HTMP4HA1MIFALDH1A1KMT2A
SCHEMBL515603 0.82 P4HTM (0.65) P4HTMP4HA1MIFKDM4EALDH1A1
SCHEMBL27623809 0.79 P4HTM (0.41) P4HTMP4HA1MIFKDM4EALDH1A1
SCHEMBL18573317 0.78 P4HTM (0.71) P4HTMP4HA1MIFKDM4EALDH1A1
SCHEMBL3242056 0.78 MAPK1 (0.59) P4HTMKDM4EALDH1A1L3MBTL1LMNA
SCHEMBL8266390 0.77 GABRA1 (0.43) P4HTMKDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL128459 0.76 P4HTM (0.67) P4HTMP4HA1MIFKDM4EALDH1A1
SCHEMBL10432643 0.76 P4HTM (0.62) P4HTMP4HA1MIFKDM4EALDH1A1
SCHEMBL9000504 0.76 P4HTM (0.67) P4HTMP4HA1MIFKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078113-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORP (US) 2026-03-19 US disclosed
US-12516044-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2026-01-06 US disclosed
EP-4353759-A1 PRODUCTION METHOD FOR AQUEOUS FLUORINE-CONTAINING ELASTOMER DISPERSION, COMPOSITION, AND AQUEOUS DISPERSION Daikin Industries, Ltd. (JP) 2024-04-17 EP disclosed
CN-117529511-A Method for producing aqueous dispersion of fluoroelastomer, composition, and aqueous dispersion 大金工业株式会社 2024-02-06 CN disclosed
US-20230192924-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION AND FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION DAIKIN INDUSTRIES, LTD. (JP) 2023-06-22 US disclosed
EP-4194474-A1 METHOD FOR PRODUCING AQUEOUS DISPERSION OF FLUORINE-CONTAINING ELASTOMER Daikin Industries, Ltd. (JP) 2023-06-14 EP disclosed
EP-4186932-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION AND FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION Daikin Industries, Ltd. (JP) 2023-05-31 EP disclosed
CN-116171291-A Method for producing aqueous dispersion of fluoroelastomer, and aqueous dispersion of fluoroelastomer 大金工业株式会社 2023-05-26 CN disclosed
WO-2022260139-A1 PRODUCTION METHOD FOR AQUEOUS FLUORINE-CONTAINING ELASTOMER DISPERSION, COMPOSITION, AND AQUEOUS DISPERSION ダイキン工業株式会社 2022-12-15 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2009055828-A1 NEW TETRACYCLIC COMPOUNDS MEDIVATION TECHNOLOGIES, INC. (US) 2009-04-30 WO disclosed
US-20090096353-A1 LIGHT EMITTING POLYMER MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY DEVICE COMPRISING LIGHT EMITTING POLYMER MATERIAL SHOWA DENKO K.K. (JP) 2009-04-16 US disclosed
EP-1902076-A1 LIGHT EMITTING POLYMER MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY DEVICE COMPRISING LIGHT EMITTING POLYMER MATERIAL Showa Dendo K.K. (JP) 2008-03-26 EP disclosed
US-20080070928-A1 Novel 2-Heteroaryl-Substituted Benzimidazole Derivative MSD K.K. (JP) 2008-03-20 US disclosed
CN-1926127-A Novel 2-heteroaryl substituted benzimidazole derivatives BANYU PHARMA CO LTD (JP) 2007-03-07 CN disclosed
WO-2006135076-A1 LIGHT EMITTING POLYMER MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY DEVICE COMPRISING LIGHT EMITTING POLYMER MATERIAL SHOWA DENKO K.K. (JP) 2006-12-21 WO disclosed
EP-1702919-A1 NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-09-20 EP disclosed
WO-2006056930-A2 NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS ACTELION PHARMACEUTICALS LTD (CH) 2006-06-01 WO disclosed
EP-1484381-A1 PHOSPHORS, PROCESS FOR PRODUCTION THEREOF, PHOSPHORESCENT COMPOSITIONS AND ARTICLES MADE BY USING THE SAME JSR Corporation (JP) 2004-12-08 EP disclosed
US-20040106006-A1 Phosphors, process for production thereof, phosphorescent compositions and articles made by using the same JSR CORPORATION (JP) 2004-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080070928-A1 Novel 2-Heteroaryl-Substituted Benzimidazole Derivative GCK, GCKR, HK1 P4HTM 4396/4885P4HA1 2836/4885MIF 2704/4885
US-20260078113-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS MSR1, NR3C1, CCR1 P4HTM 3649/4885P4HA1 1945/4885MIF 897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.