Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836799 | 0.91 | GPR35 (0.55) | ALDH1A1GAAHPGDGPR35LMNA | |
| SCHEMBL1285514 | 0.85 | MAPT (0.56) | ALDH1A1GAAHPGDGPR35LMNA | |
| SCHEMBL6488967 | 0.85 | ALDH1A1 (0.49) | ALDH1A1GAAHPGDGPR35LMNA | |
| SCHEMBL12225198 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDGPR35LMNA | |
| SCHEMBL29722774 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDLMNASMN1; SMN2 | |
| SCHEMBL27883929 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDGPR35LMNA | |
| SCHEMBL1632654 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDLMNASMN1; SMN2 | |
| SCHEMBL405926 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDGPR35LMNA | |
| SCHEMBL3300905 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDLMNASMN1; SMN2 | |
| SCHEMBL638498 | 0.83 | TSHR (0.54) | ALDH1A1GAAHPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621111-A | Mild synthesis method of 4-acetamido-5-nitro-m-xylene | 李期林 | 2022-06-14 | — | — | CN | claimed |
| US-4540817-A | Process for the preparation of 5-amino-2,4-dimethylacetanilide | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | claimed |
| EP-0054809-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-2,4 DIMETHYLACETANILIDE | BAYER AG (DE) | 1984-05-23 | — | — | EP | claimed |
| EP-0054809-A1 | Process for the preparation of 5-amino-2,4 dimethylacetanilide | BAYER AG (DE) | 1982-06-30 | — | — | EP | claimed |
| CN-114621111-A | Mild synthesis method of 4-acetamido-5-nitro-m-xylene | 李期林 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621111-A | Mild synthesis method of 4-acetamido-5-nitro-m-xylene | 李期林 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621111-A | Mild synthesis method of 4-acetamido-5-nitro-m-xylene | 李期林 | 2022-06-14 | — | — | CN | disclosed |
| CN-101679299-A | Nicotinic acid derivatives as modulators of metabotropic glutamate receptor-5 | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |
| EP-2146969-A1 | NICOTINIC ACID DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 | Novartis Ag (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-20090105266-A1 | Organic compounds | NOVARTIS AG (CH) | 2009-04-23 | — | — | US | disclosed |
| WO-2008128968-A1 | NICOTINIC ACID DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 | NOVARTIS AG (CH) | 2008-10-30 | — | — | WO | disclosed |
| US-4540817-A | Process for the preparation of 5-amino-2,4-dimethylacetanilide | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0054809-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-2,4 DIMETHYLACETANILIDE | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| EP-0054809-A1 | Process for the preparation of 5-amino-2,4 dimethylacetanilide | BAYER AG (DE) | 1982-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105266-A1 | Organic compounds | SLCO2B1, SLCO1B1, SLCO1B3 | ALDH1A1 45/4885GAA 597/4885HPGD 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.