Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4344919 | 0.92 | CHRM2 (0.47) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL6098673 | 0.88 | MAPT (0.52) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL5354341 | 0.86 | CHRM2 (0.44) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL18587552 | 0.86 | MAPT (0.50) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL6493971 | 0.86 | POLB (0.54) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL5358407 | 0.85 | CHRM2 (0.48) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL4321129 | 0.84 | ADRA1A (0.50) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL9603172 | 0.84 | MAPT (0.54) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL6718844 | 0.84 | MAPT (0.50) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL2888870 | 0.84 | POLB (0.56) | CHRM2CHRM1DRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353609-B | Amide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO | 2011-07-13 | — | — | CN | disclosed |
| EP-2155743-A1 | IMIDAZOQUINOLINES WITH IMMUNO-MODULATING PROPERTIES | AstraZeneca AB (SE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008135791-A1 | IMIDAZOQUINOLINES WITH IMMUNO-MODULATING PROPERTIES | ASTRAZENECA AB (SE) | 2008-11-13 | — | — | WO | disclosed |
| CN-1353609-A | Amide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2002-06-12 | — | — | CN | disclosed |