Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 20/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650359 | 0.76 | CTSA (0.36) | CTSA | |
| SCHEMBL11822720 | 0.74 | CTSA (0.36) | CTSA | |
| SCHEMBL8041258 | 0.74 | — | — | |
| SCHEMBL24327736 | 0.72 | CTSA (0.40) | CTSA | |
| SCHEMBL24328842 | 0.72 | CTSA (0.40) | CTSA | |
| SCHEMBL1827574 | 0.72 | FAAH (0.36) | CTSA | |
| SCHEMBL17337936 | 0.71 | SLC7A5 (0.38) | CTSA | |
| SCHEMBL17337934 | 0.71 | SLC7A5 (0.38) | CTSA | |
| SCHEMBL6426003 | 0.71 | CYP2D6 (0.44) | CTSA | |
| SCHEMBL8061000 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101835757-B | Diacylglycerol acyltransferase inhibitors | HOFFMANN LA ROCHE | 2014-03-05 | — | — | CN | disclosed |
| CN-101835757-A | Diacylglycerol acyltransferase inhibitors | HOFFMANN LA ROCHE | 2010-09-15 | — | — | CN | disclosed |
| EP-2155687-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008141976-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |