Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 14/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475689 | 0.86 | FAAH (0.38) | FAAHCES1CTSA | |
| SCHEMBL6607172 | 0.83 | FAAH (0.42) | FAAHCES1CTSA | |
| SCHEMBL4340142 | 0.79 | HKDC1 (0.38) | CTSA | |
| SCHEMBL4329821 | 0.77 | FFAR2 (0.41) | CTSAAKR1C3AKR1C2 | |
| SCHEMBL4331353 | 0.77 | CTSA (0.41) | CTSA | |
| SCHEMBL4328044 | 0.77 | MEN1 (0.32) | FAAHCES1CTSA | |
| SCHEMBL1650359 | 0.76 | CTSA (0.36) | CTSA | |
| SCHEMBL4327338 | 0.75 | FFAR1 (0.48) | FAAHCTSAAKR1C3AKR1C2 | |
| SCHEMBL4327553 | 0.75 | CTSA (0.41) | CTSA | |
| SCHEMBL9452969 | 0.74 | CYP1A2 (0.40) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4685307-B2 | — | — | 2011-05-18 | — | — | JP | claimed |
| JP-2003508516-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1218005-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-09 | — | — | EP | claimed |
| EP-1218005-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-07-03 | — | — | EP | claimed |
| WO-2001017959-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-15 | — | — | WO | claimed |
| CN-113226368-A | Neurological disease treatment with zilucoprol | RA制药公司 | 2021-08-06 | — | — | CN | disclosed |
| EP-1102587-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1218005-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1218005-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1102587-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2001017959-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-15 | — | — | WO | disclosed |
| WO-2000007544-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-17 | — | — | WO | disclosed |