SCHEMBL3635955

SCHEMBL3635955

[O]c1ccccc1OC1=CC=CCC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11047999 0.80 HTR1A (0.39)
SCHEMBL5139099 0.79
SCHEMBL2186316 0.70 CA12 (0.38)
SCHEMBL11812594 0.69
SCHEMBL11774992 0.65 LMNA (0.47)
SCHEMBL10822242 0.64
SCHEMBL10334721 0.64
SCHEMBL9070304 0.63 SMN1; SMN2 (0.52)
SCHEMBL10937420 0.63
SCHEMBL547088 0.63 GLA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230125630-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF UNIV MARYLAND (US) 2023-04-27 US disclosed
US-11584828-B2 Polyphosphazene polyelectrolytes and uses thereof UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2023-02-21 US disclosed
US-11472927-B2 Polyphosphazenes, methods of making, and uses thereof UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2022-10-18 US disclosed
US-20210087342-A1 POLYPHOSPHAZENE POLYELECTROLYTES AND USES THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK 2021-03-25 US disclosed
US-10858483-B2 Polyphosphazene polyelectrolytes and uses thereof UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2020-12-08 US disclosed
US-20190352468-A1 POLYPHOSPHAZENE POLYELECTROLYTES AND USES THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK 2019-11-21 US disclosed
US-20180327550-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK 2018-11-15 US disclosed
EP-3377560-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF University of Maryland, College Park (US) 2018-09-26 EP disclosed
WO-2018009672-A1 POLYPHOSPHAZENE POLYELECTROLYTES AND USES THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2018-01-11 WO disclosed
EP-2173431-A1 IMMUNOSTIMULATING POLYPHOSPHAZENE COMPOUNDS FOR INTRADERMAL IMMUNIZATION Apogee Technology, Inc. (US) 2010-04-14 EP disclosed
EP-2167131-A1 COATING FORMULATIONS INCLUDING POLYPHOSPHAZENE POLYELECTROLYTES AND BIOLOGICALLY ACTIVE AGENTS AND ASPERITIES COATED WITH SUCH FORMULATIONS Apogee Technology, Inc. (US) 2010-03-31 EP disclosed
US-20090041810-A1 Immunostimulating polyphosphazene compounds for intradermal immunization ANDRIANOV ALEXANDER K 2009-02-12 US disclosed
WO-2009008988-A1 IMMUNOSTIMULATING POLYPHOSPHAZENE COMPOUNDS FOR INTRADERMAL IMMUNIZATION APOGEE TECHNOLOGY, INC. (US) 2009-01-15 WO disclosed
WO-2009009004-A1 COATING FORMULATIONS INCLUDING POLYPHOSPHAZENE POLYELECTROLYTES AND BIOLOGICALLY ACTIVE AGENTS AND ASPERITIES COATED WITH SUCH FORMULATIONS APOGEE TECHNOLOGY, INC. (US) 2009-01-15 WO disclosed
US-20090016935-A1 Coating formulations including polyphosphazene polyelectrolytes and biologically active agents and asperities coated with such formulations ANDRIANOV ALEXANDER K 2009-01-15 US disclosed