Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404066 | 0.97 | EPHX1 (0.40) | EPHX1SHBGALDH1A1TP53KDM4E | |
| SCHEMBL2999144 | 0.97 | EPHX1 (0.40) | EPHX1SHBGALDH1A1TP53KDM4E | |
| SCHEMBL9081302 | 0.95 | EPHX1 (0.33) | EPHX1SHBGALDH1A1TP53 | |
| SCHEMBL10999166 | 0.83 | ALDH1A1 (0.38) | EPHX1SHBGALDH1A1TP53KDM4E | |
| SCHEMBL8816076 | 0.83 | EPHX1 (0.34) | EPHX1SHBGALDH1A1TP53LMNA | |
| SCHEMBL16191183 | 0.83 | SHBG (0.50) | EPHX1SHBGALDH1A1TP53 | |
| SCHEMBL10999554 | 0.80 | ALDH1A1 (0.36) | EPHX1SHBGALDH1A1TP53KDM4E | |
| SCHEMBL8027763 | 0.77 | SHBG (0.30) | SHBG | |
| SCHEMBL2988423 | 0.76 | EPHX1 (0.52) | EPHX1SHBGALDH1A1TP53LMNA | |
| SCHEMBL15703452 | 0.76 | EPHX1 (0.52) | EPHX1SHBGALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155719-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | Wyeth LLC (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008147945-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-12-04 | — | — | WO | disclosed |