SCHEMBL3636037

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27933650	0.87	IRAK4 (0.56)	IRAK4ALDH1A1EZH2KDM4ETDP1
	SCHEMBL27370629	0.84	IRAK4 (0.72)	IRAK4ALDH1A1EZH2KCNK3KCNK9
	SCHEMBL4857330	0.83	PTGER1 (0.45)	ALDH1A1EZH2KDM4EHPGDHSD17B10
	SCHEMBL16954345	0.83	IRAK4 (0.50)	IRAK4ALDH1A1EZH2TDP1KCNK3
	SCHEMBL104892	0.83	IRAK4 (0.70)	IRAK4ALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL15814203	0.83	IRAK4 (0.51)	IRAK4ALDH1A1EZH2KDM4EHPGD
	SCHEMBL30625923	0.82	IRAK4 (0.54)	IRAK4ALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL27747076	0.82	IRAK4 (0.54)	IRAK4ALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL1818841	0.82	IRAK4 (0.54)	IRAK4ALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL10763308	0.81	IRAK4 (0.68)	IRAK4ALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.