Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656727 | 0.92 | LMNA (0.61) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL10658512 | 0.92 | LMNA (0.61) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL10894160 | 0.92 | LMNA (0.61) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL1517925 | 0.86 | LMNA (0.58) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL7732782 | 0.81 | KDM4C (0.49) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL3306771 | 0.81 | LMNA (0.89) | LMNAKDM4CCA1NPC1TSHR | |
| SCHEMBL12410119 | 0.79 | LMNA (0.50) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL2570952 | 0.79 | KDM4C (0.50) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL13630657 | 0.79 | LMNA (0.84) | LMNANPC1TSHRHPGDRAB9A | |
| SCHEMBL21886876 | 0.77 | LMNA (0.48) | LMNAKDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170813-A2 | A NOVEL PROCESS FOR THE PREPARATION OF PREGABALIN | Satyanarayana Reddy, Manne (IN) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009001372-A2 | A NOVEL PROCESS FOR THE PREPARATION OF PREGABALIN | SATYANARAYANA REDDY MANNE (IN) | 2008-12-31 | — | — | WO | disclosed |