SCHEMBL3636324

SCHEMBL3636324

CC(O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYNJ2 O15056 2/20 0.59
KDM4E B2RXH2 1/20 0.59
ABL1 P00519 1/20 0.59
ALPL P05186 1/20 0.59
POLB P06746 1/20 0.59
ALPI P09923 1/20 0.59
GAA P10253 1/20 0.59
MAPT P10636 1/20 0.59
ALPG P10696 1/20 0.59
PABPC1 P11940 1/20 0.59
RECQL P46063 1/20 0.59
GALK1 P51570 1/20 0.59
CASP7 P55210 1/20 0.59
CASP6 P55212 1/20 0.59
MCL1 Q07820 1/20 0.59
RIN1 Q13671 1/20 0.59
EIF4H Q15056 1/20 0.59
CD209 Q9NNX6 3/20 0.57
TYR P14679 2/20 0.49
PPARG P37231 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5336720 0.92 SYNJ2 (0.53) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL1239221 0.92 SYNJ2 (0.53) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL28707080 0.87 PPARG (0.60) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL28007620 0.87 PPARG (0.60) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL28707074 0.86 TACR1 (0.55) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL28712353 0.85 TYR (0.56) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL24837353 0.85 SYNJ2 (0.55) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL8604757 0.85 SYNJ2 (0.55) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL8718358 0.85 SYNJ2 (0.55) SYNJ2KDM4EABL1ALPLPOLB
SCHEMBL4984171 0.85 SYNJ2 (0.55) SYNJ2KDM4EABL1ALPLPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100330596-A1 LIPOPROTEIN SURFACTANT ROCHE DIABETES CARE, INC. 2010-12-30 US disclosed
EP-2164982-A2 LIPOPROTEIN SURFACTANT F.HOFFMANN-LA ROCHE AG (CH) 2010-03-24 EP disclosed
WO-2008152380-A2 LIPOPROTEIN SURFACTANT OXFORD BIOSENSORS LIMITED (GB) 2008-12-18 WO disclosed