SCHEMBL5336720

SCHEMBL5336720

CC(O[C@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYNJ2 O15056 2/20 0.53
GAA P10253 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ABL1 P00519 1/20 0.53
ALPL P05186 1/20 0.53
POLB P06746 1/20 0.53
ALPI P09923 1/20 0.53
MAPT P10636 1/20 0.53
ALPG P10696 1/20 0.53
PABPC1 P11940 1/20 0.53
RECQL P46063 1/20 0.53
GALK1 P51570 1/20 0.53
CASP7 P55210 1/20 0.53
CASP6 P55212 1/20 0.53
MCL1 Q07820 1/20 0.53
RIN1 Q13671 1/20 0.53
EIF4H Q15056 1/20 0.53
CD209 Q9NNX6 3/20 0.51
ACHE P22303 1/20 0.46
CDK1 P06493 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1239221 1.00 SYNJ2 (0.53) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL3636324 0.92 SYNJ2 (0.59) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL1239229 0.90 SYNJ2 (0.43) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL1239269 0.86 SYNJ2 (0.46) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL1238467 0.86 SYNJ2 (0.46) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL29624136 0.85 PTPN1 (0.54) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL1238270 0.85 SYNJ2 (0.45) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL1238269 0.85 SYNJ2 (0.45) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL1239131 0.84 SYNJ2 (0.52) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL1238535 0.84 SYNJ2 (0.52) SYNJ2GAAKDM4EABL1ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847270-A1 USE OF AMYGDALIN ANALOGUES FOR THE TREATMENT OF PSORIASIS Universitat Politecnica de Catalunya (ES) 2007-10-24 EP disclosed