Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808573 | 0.87 | MEN1 (0.45) | MEN1KMT2AGPR6EPHX2RORC | |
| SCHEMBL2808569 | 0.87 | MEN1 (0.45) | MEN1KMT2AGPR6EPHX2RORC | |
| SCHEMBL3638997 | 0.83 | HCRTR1 (0.39) | ADAM17MMP1HCRTR1HCRTR2MEN1 | |
| SCHEMBL13167738 | 0.73 | P4HB (0.41) | ADAM17MMP1HCRTR1HCRTR2EPHX2 | |
| SCHEMBL13130722 | 0.71 | EPHX2 (0.44) | MEN1KMT2AEPHX2LIPEMMP13 | |
| SCHEMBL2811084 | 0.68 | MEN1 (0.44) | HCRTR1HCRTR2MEN1KMT2AGPR6 | |
| SCHEMBL2811082 | 0.68 | MEN1 (0.44) | HCRTR1HCRTR2MEN1KMT2AGPR6 | |
| SCHEMBL2811085 | 0.68 | MEN1 (0.44) | HCRTR1HCRTR2MEN1KMT2AGPR6 | |
| SCHEMBL2810663 | 0.68 | EPHX2 (0.44) | MEN1KMT2AGPR6EPHX2SFRP1 | |
| SCHEMBL8118131 | 0.68 | EPHX2 (0.44) | MEN1KMT2AGPR6EPHX2SFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164325-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | Shionogi&Co., Ltd. (JP) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150470-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-12-11 | — | — | WO | disclosed |