Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811084 | 0.87 | MEN1 (0.44) | HCRTR1HCRTR2GPR6MMP13MEN1 | |
| SCHEMBL2811085 | 0.87 | MEN1 (0.44) | HCRTR1HCRTR2GPR6MMP13MEN1 | |
| SCHEMBL2811082 | 0.87 | MEN1 (0.44) | HCRTR1HCRTR2GPR6MMP13MEN1 | |
| SCHEMBL3636331 | 0.83 | ADAM17 (0.38) | HCRTR1HCRTR2MMP1ADAM17GPR6 | |
| SCHEMBL8118131 | 0.77 | EPHX2 (0.44) | GPR6MMP13MEN1KMT2AAKR1C3 | |
| SCHEMBL2810661 | 0.77 | EPHX2 (0.44) | GPR6MMP13MEN1KMT2AAKR1C3 | |
| SCHEMBL2810663 | 0.77 | EPHX2 (0.44) | GPR6MMP13MEN1KMT2AAKR1C3 | |
| SCHEMBL13167796 | 0.74 | LMNA (0.40) | HCRTR1HCRTR2MEN1KMT2ARORC | |
| SCHEMBL13130724 | 0.73 | EPHX2 (0.43) | MMP13MEN1KMT2A | |
| SCHEMBL1677066 | 0.71 | GPR6 (0.48) | HCRTR1HCRTR2GPR6MMP13MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164325-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | Shionogi&Co., Ltd. (JP) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150470-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-12-11 | — | — | WO | disclosed |