Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.52 |
| ▸ | GAK | O14976 | 2/20 | 0.52 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.52 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631574 | 0.90 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BRIPK2 | |
| SCHEMBL29862969 | 0.90 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BRIPK2 | |
| SCHEMBL3631572 | 0.90 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BRIPK2 | |
| Hydrochloric Acid SCHEMBL23360528 | 0.89 | HTR1A (0.51) | HTR1AADRA1DADRA1AADRA1BRIPK2 | |
| Hydrochloric Acid SCHEMBL23360525 | 0.89 | HTR1A (0.51) | HTR1AADRA1DADRA1AADRA1BRIPK2 | |
| SCHEMBL4752616 | 0.82 | HTR1A (0.57) | HTR1AADRA1DADRA1AADRA1BRIPK2 | |
| SCHEMBL3634020 | 0.81 | MTNR1B (0.47) | LMNAKDM4EMTNR1AMTNR1BMAPK1 | |
| SCHEMBL3630852 | 0.81 | NQO2 (0.61) | MAPK1 | |
| SCHEMBL29862805 | 0.80 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BRIPK2 | |
| Hydrochloric Acid SCHEMBL23360615 | 0.79 | HTR1A (0.53) | HTR1AADRA1DADRA1AADRA1BRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |