Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CALML3 | P27482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634321 | 0.96 | MAOA (0.32) | MAOACALML3ALDH1A1HTT | |
| SCHEMBL3629846 | 0.93 | MAOA (0.32) | MAOACALML3ALDH1A1HTTMAOB | |
| SCHEMBL3633094 | 0.86 | KCNH2 (0.38) | MAOAMAOBKCNH2 | |
| SCHEMBL3633217 | 0.84 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL3636351 | 0.83 | KCNH2 (0.40) | MAOAMAOBKCNH2 | |
| SCHEMBL634111 | 0.77 | SIGMAR1 (0.36) | MAOACALML3TRPV1MAOBKCNH2 | |
| SCHEMBL633769 | 0.77 | SIGMAR1 (0.36) | MAOACALML3TRPV1MAOBKCNH2 | |
| SCHEMBL1224655 | 0.77 | MAOA (0.34) | MAOACALML3TRPV1MAOBKCNH2 | |
| SCHEMBL1224657 | 0.77 | MAOA (0.34) | MAOACALML3TRPV1MAOBKCNH2 | |
| SCHEMBL1224247 | 0.77 | MAOB (0.36) | MAOACALML3TRPV1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |