Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087946 | 0.90 | MET (0.53) | MET | |
| SCHEMBL3087125 | 0.82 | MET (0.59) | MET | |
| SCHEMBL3631469 | 0.80 | PIK3CA (0.42) | — | |
| SCHEMBL16087431 | 0.79 | MET (0.57) | MET | |
| SCHEMBL16087481 | 0.78 | MET (0.59) | MET | |
| SCHEMBL3943542 | 0.78 | MET (0.60) | MET | |
| SCHEMBL3667693 | 0.77 | MET (0.48) | MET | |
| SCHEMBL3634219 | 0.75 | MET (0.52) | MET | |
| SCHEMBL13089755 | 0.75 | MET (0.62) | MET | |
| SCHEMBL3942030 | 0.75 | MET (0.48) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2754660-B1 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2164843-B1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | disclosed |
| EP-2164843-A1 | PYRIDAZINONE DERIVATES | Merck Patent GmbH (DE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009006959-A1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |