Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090940 | 0.90 | MET (0.49) | METNQO2HDAC1 | |
| SCHEMBL3095953 | 0.85 | MET (0.57) | METNQO2 | |
| SCHEMBL3081927 | 0.82 | MET (0.56) | METNQO2 | |
| SCHEMBL2348812 | 0.79 | MET (0.62) | METHDAC1 | |
| SCHEMBL3631784 | 0.79 | GPR119 (0.38) | — | |
| SCHEMBL12239820 | 0.79 | MET (0.57) | METNQO2HDAC1 | |
| SCHEMBL13152656 | 0.78 | MET (0.71) | MET | |
| SCHEMBL3079125 | 0.77 | MET (0.63) | METNQO2 | |
| SCHEMBL2347766 | 0.77 | MET (0.62) | MET | |
| SCHEMBL3095826 | 0.77 | MET (0.62) | METHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2754660-B1 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2164843-B1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | disclosed |
| EP-2164843-A1 | PYRIDAZINONE DERIVATES | Merck Patent GmbH (DE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009006959-A1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |