SCHEMBL3636657

SCHEMBL3636657

[c]1ccn(-c2cccs2)c1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141173 0.73 POLB (0.41) FBP1
SCHEMBL27656935 0.72 SMN1; SMN2 (0.40) FBP1
Thiophene SCHEMBL10591457 0.67 SMN1; SMN2 (0.37) FBP1
SCHEMBL4794019 0.67 KMT2A (0.33)
SCHEMBL25457541 0.64 MEN1 (0.35)
Pyridine SCHEMBL27784037 0.64 CYP3A4 (0.38)
SCHEMBL558211 0.63 GRM4 (0.35)
SCHEMBL27590600 0.63 CYP3A4 (0.47)
SCHEMBL30898337 0.62 CYP3A4 (0.39)
SCHEMBL2635747 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4334350-A1 BMA031 ANTIGEN BINDING POLYPEPTIDES Immatics Biotechnologies GmbH (DE) 2024-03-13 EP disclosed
US-11851489-B2 Heterodimerizing Ig domains Universität Stuttgart (DE) 2023-12-26 US disclosed
WO-2022233957-A1 BMA031 ANTIGEN BINDING POLYPEPTIDES IMMATICS BIOTECHNOLOGIES GMBH (DE) 2022-11-10 WO disclosed
US-20210155660-A1 RATIONALLY DESIGNED VIRUS-LIKE PARTICLES FOR MODULATION OF CHIMERIC ANTIGEN RECEPTOR (CAR)-T-CELL THERAPY Ruprecht-Karls-Universität Heidelberg (DE) 2021-05-27 US disclosed
US-11008402-B2 Antigen binding protein against HER3 UNIVERSITAT STUTTGART 2021-05-18 US disclosed
US-20200384028-A1 SORTING WITH COUNTER SELECTION USING SEQUENCE SIMILAR PEPTIDES IMMATICS BIOTECHNOLOGIES GMBH (DE) 2020-12-10 US disclosed
WO-2020245326-A1 SORTING WITH COUNTER SELECTION USING SEQUENCE SIMILAR PEPTIDES IMMATICS BIOTECHNOLOGIES GMBH (DE) 2020-12-10 WO disclosed
EP-3676284-A1 RATIONALLY DESIGNED VIRUS-LIKE PARTICLES FOR MODULATION OF CHIMERIC ANTIGEN RECEPTOR (CAR)-T-CELL THERAPY Ruprecht-Karls-Universität Heidelberg (DE) 2020-07-08 EP disclosed
US-20200172619-A1 HETERODIMERIZING IG DOMAINS Universität Stuttgart (DE) 2020-06-04 US disclosed
EP-3630811-A1 HETERODIMERIZING IG DOMAINS Universität Stuttgart (DE) 2020-04-08 EP disclosed
US-20190252037-A1 Viral Polypeptide Fragments That Bind Cellular POL II C-Terminal Domain (CTD) and Their Uses THE EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2019-08-15 US disclosed
US-20190194350-A1 ANTIGEN BINDING PROTEIN AGAINST HER3 UNIV STUTTGART (DE) 2019-06-27 US disclosed
EP-3481946-A1 VIRAL POLYPEPTIDE FRAGMENTS THAT BIND CELLULAR POL II C-TERMINAL DOMAIN (CTD) AND THEIR USES The European Molecular Biology Laboratory (DE) 2019-05-15 EP disclosed
WO-2019043081-A1 RATIONALLY DESIGNED VIRUS-LIKE PARTICLES FOR MODULATION OF CHIMERIC ANTIGEN RECEPTOR (CAR)-T-CELL THERAPY Ruprecht-Karls-Universität Heidelberg (DE) 2019-03-07 WO disclosed
WO-2018220216-A1 HETERODIMERIZING IG DOMAINS Universität Stuttgart (DE) 2018-12-06 WO disclosed
WO-2018007615-A1 VIRAL POLYPEPTIDE FRAGMENTS THAT BIND CELLULAR POL II C-TERMINAL DOMAIN (CTD) AND THEIR USES THE EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2018-01-11 WO disclosed
EP-2164955-B1 MUTANT DNA POLYMERASES AND RELATED METHODS ROCHE DIAGNOSTICS GMBH (DE) 2013-03-06 EP disclosed
EP-2164955-A2 MUTANT DNA POLYMERASES AND RELATED METHODS Roche Diagnostics GmbH (DE) 2010-03-24 EP disclosed
WO-2009010251-A2 MUTANT DNA POLYMERASES AND RELATED METHODS ROCHE DIAGNOSTICS GMBH (DE) 2009-01-22 WO disclosed