SCHEMBL141173

SCHEMBL141173

c1csc(-n2cccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
GAA P10253 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
FBP1 P09467 1/20 0.35
KDM4E B2RXH2 4/20 0.33
HSD17B10 Q99714 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL10591457 0.91 SMN1; SMN2 (0.37) POLBSMN1; SMN2GAAMEN1KMT2A
SCHEMBL4794019 0.81 KMT2A (0.33) POLBSMN1; SMN2GAAMEN1KMT2A
SCHEMBL25457541 0.73 MEN1 (0.35) POLBSMN1; SMN2GAAMEN1KMT2A
SCHEMBL7644186 0.73 CYP3A4 (0.48) GAAMEN1KMT2AMAPTCYP1A2
SCHEMBL3636657 0.73 FBP1 (0.32) FBP1
SCHEMBL30898337 0.71 CYP3A4 (0.39) POLBSMN1; SMN2GAAMEN1KMT2A
SCHEMBL3082360 0.69 KDM4E (0.35) POLBGAAMEN1KMT2AMAPT
SCHEMBL9471238 0.69 TSHR (0.46) POLBSMN1; SMN2KMT2AMAPTCYP3A4
SCHEMBL2635747 0.68
SCHEMBL13045102 0.68 CYP2E1 (0.46) POLBSMN1; SMN2GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4104 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4648851-A1 SUBSTITUTED (HETERO)ANILINES AND THEIR USE Astrazeneca AB (SE) 2025-11-19 EP claimed
CN-119943910-A Modified lithium-rich manganese-based positive electrode material and preparation method and application thereof 孝感楚能新能源创新科技有限公司 2025-05-06 CN claimed
CN-119522228-A Electron transport material, perovskite solar cell and electricity utilization device 宁德时代新能源科技股份有限公司 2025-02-25 CN claimed
CN-116063320-B Scorpion type undoped organic micromolecular hole transport material and preparation method and application thereof 江西师范大学 2025-02-07 CN claimed
WO-2025011316-A1 SOLAR CELL AND PREPARATION METHOD THEREFOR, PHOTOVOLTAIC MODULE, SYSTEM AND ELECTRIC DEVICE 宁德时代未来能源(上海)研究院有限公司 2025-01-16 WO claimed
CN-119277884-A Solar cell, preparation method thereof, photovoltaic module, system and power utilization device 宁德时代未来能源(上海)研究院有限公司 2025-01-07 CN claimed
CN-119183303-A Perovskite solar cell and preparation method and application thereof 宁德时代未来能源(上海)研究院有限公司 2024-12-24 CN claimed
US-20240366807-A1 RADIOFLUORINATED AGENTS FOR PET IMAGING SELECTIVELY TARGETING FIBROBLAST ACTIVATION PROTEIN TRUSTEES OF TUFTS COLLEGE 2024-11-07 US claimed
US-12133453-B2 Polymer, composition for organic electroluminescent element, organic electroluminescent element, organic EL display device, organic EL lighting, and manufacturing method for organic electroluminescent element MITSUBISHI CHEMICAL CORPORATION (JP) 2024-10-29 US claimed
CN-118791841-A Composite material, light-emitting device, preparation method of light-emitting device and display device TCL科技集团股份有限公司 2024-10-18 CN claimed
WO-1995019171-A1 METHOD FOR TREATING DISEASES MEDIATED BY CELLULAR PROLIFERATION IN RESPONSE TO PDGF, EGF, FGF AND VEGF CELL THERAPEUTICS, INC. (US) 1995-07-20 WO claimed
WO-1995013075-A1 METHOD FOR PREVENTING TISSUE INJURY FROM HYPOXIA CELL THERAPEUTICS, INC. (US) 1995-05-18 WO claimed
WO-1995012396-A1 METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION CELL THERAPEUTICS, INC. (US) 1995-05-11 WO claimed
EP-0269090-B1 Highly conductive polymer composition and process for producing the same SHOWA DENKO KK (JP) 1994-02-02 EP claimed
EP-0261755-B1 FIVE-MEMBERED HETEROCYCLIC DERIVATIVES OF N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1992-12-16 EP claimed
US-5057406-A Aging stability, spectral sensitizers KONICA CORPORATION (JP) 1991-10-15 US claimed
EP-0341958-A2 Silver halide photographic material KONICA CORPORATION (JP) 1989-11-15 EP claimed
US-4864472-A Solid electrolyte capacitor MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-09-05 US claimed
EP-0269090-A1 Highly conductive polymer composition and process for producing the same SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-06-01 EP claimed
EP-0261755-A2 Five-membered heterocyclic derivatives of N'-substituted-N,N'-Diacylhydrazines ROHM AND HAAS COMPANY (US) 1988-03-30 EP claimed