Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988174 | 1.00 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| Iomeprol SCHEMBL26981 | 0.95 | LMNA (0.63) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9735781 | 0.92 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL14790186 | 0.91 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9389731 | 0.91 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL15849020 | 0.90 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9736390 | 0.89 | LMNA (0.57) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9237281 | 0.88 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL22661240 | 0.88 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9238059 | 0.88 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593423-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | Bracco Imaging S.p.A (IT) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007547-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2012-01-19 | — | — | WO | disclosed |