Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238059 | 1.00 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL15988174 | 0.88 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL363705 | 0.88 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8377986 | 0.87 | LMNA (0.63) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9563916 | 0.86 | LMNA (0.62) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9232583 | 0.84 | CYP2C19 (0.70) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL11292903 | 0.84 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9236621 | 0.83 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL13944447 | 0.83 | LMNA (0.72) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9009233 | 0.82 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673922-A1 | Non-ionic iodinated dimers as X-ray contrast agents, process for their preparation and pharmaceutical compositions containing them | CENTRO INVESTIGACION JUSTESA IMAGEN S.A. (ES) | 1995-09-27 | — | — | EP | claimed |
| EP-0673922-A1 | Non-ionic iodinated dimers as X-ray contrast agents, process for their preparation and pharmaceutical compositions containing them | CENTRO INVESTIGACION JUSTESA IMAGEN S.A. (ES) | 1995-09-27 | — | — | EP | disclosed |