Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 6/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 6/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81056 | 0.89 | NR3C2 (0.47) | NR3C2PTPN7DUSP3KIF11USP28 | |
| SCHEMBL25185197 | 0.85 | KIF11 (0.59) | NR3C2KIF11KDM4EALDH1A1ALOX5 | |
| SCHEMBL10299813 | 0.84 | KIF11 (0.58) | NR3C2PTPN7DUSP3KIF11USP28 | |
| SCHEMBL29875866 | 0.84 | KIF11 (0.58) | NR3C2PTPN7DUSP3KIF11USP28 | |
| SCHEMBL93061 | 0.84 | KIF11 (0.58) | NR3C2PTPN7DUSP3KIF11USP28 | |
| SCHEMBL3244152 | 0.82 | TAAR1 (0.53) | NR3C2PTPN7DUSP3KDM4EALDH1A1 | |
| SCHEMBL2600223 | 0.81 | CTSS (0.46) | NR3C2PTPN7DUSP3KIF11AR | |
| SCHEMBL27789311 | 0.81 | NR3C2 (0.46) | NR3C2PTPN7DUSP3KIF11USP28 | |
| Hydrochloric Acid SCHEMBL3230959 | 0.81 | TAAR1 (0.52) | NR3C2PTPN7DUSP3KDM4EALDH1A1 | |
| SCHEMBL6813477 | 0.81 | KDM4E (0.59) | KIF11KDM4EALDH1A1ALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947839-A | Amino alcohol compound, oxazoline compound, preparation method and application thereof | 中国科学院福建物质结构研究所 | 2023-10-27 | — | — | CN | disclosed |
| EP-1917250-B1 | ANTI-INFLAMMATORY ARYL NITRILE COMPOUNDS | AMGEN INC (US) | 2010-07-21 | — | — | EP | disclosed |
| CN-101781162-A | Method for preparing trifluoromethyl styrene compound | SHANGHAI CHEMEXPLORER CO LTD | 2010-07-21 | — | — | CN | disclosed |
| CN-101781161-A | Method for preparing trifluoromethyl styrene compound | SHANGHAI CHEMEXPLORER CO LTD | 2010-07-21 | — | — | CN | disclosed |
| EP-2148870-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008130584-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |