Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | CCR3 | P51677 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810661 | 0.83 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL2810663 | 0.83 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL8118131 | 0.83 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL2811085 | 0.72 | MEN1 (0.44) | HCRTR1HCRTR2EPHX2 | |
| SCHEMBL2811084 | 0.72 | MEN1 (0.44) | HCRTR1HCRTR2EPHX2 | |
| SCHEMBL2811082 | 0.72 | MEN1 (0.44) | HCRTR1HCRTR2EPHX2 | |
| SCHEMBL13167769 | 0.70 | LMNA (0.41) | HCRTR1HCRTR2EPHX2 | |
| SCHEMBL7950089 | 0.69 | CARM1 (0.39) | HCRTR1EPHX2 | |
| SCHEMBL7945321 | 0.69 | CARM1 (0.39) | HCRTR1EPHX2 | |
| SCHEMBL13130723 | 0.68 | EPHX2 (0.44) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164325-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | Shionogi&Co., Ltd. (JP) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150470-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-12-11 | — | — | WO | disclosed |