Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849266 | 0.86 | RAB9A (0.42) | GPR119RAB9ACHRM2CHRM1 | |
| SCHEMBL3132682 | 0.84 | RAB9A (0.42) | GPR119RAB9ACHRM2CHRM1 | |
| SCHEMBL458404 | 0.84 | GPR119 (0.50) | GPR119 | |
| SCHEMBL1692765 | 0.80 | RAB9A (0.46) | GPR119RAB9ACHRM2CHRM1 | |
| SCHEMBL310750 | 0.80 | GPR119 (0.57) | GPR119 | |
| SCHEMBL1841296 | 0.79 | RAB9A (0.44) | GPR119RAB9ACHRM2CHRM1 | |
| SCHEMBL3132481 | 0.79 | RAB9A (0.44) | GPR119RAB9ACHRM2CHRM1 | |
| SCHEMBL23387564 | 0.79 | GPR119 (0.38) | GPR119 | |
| SCHEMBL458216 | 0.79 | GPR119 (0.38) | GPR119 | |
| SCHEMBL5249314 | 0.78 | GPR119 (0.45) | GPR119RAB9ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |